Paralog- and ortholog-specificity of inhibitors of human and mouse lipoxygenase-isoforms
Lipoxygenases (ALOX-isoforms) are lipid peroxidizing enzymes, which have been implicated in cell differentiation and maturation but also in the biosynthesis of lipid mediators playing important roles in the pathogenesis of inflammatory, hyperproliferative and neurological diseases. In mammals these...
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Main Authors: | , , , , , |
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Format: | article |
Language: | EN |
Published: |
Elsevier
2022
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Subjects: | |
Online Access: | https://doaj.org/article/ceedff28c8c34ca48c9278f1abd92056 |
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