FOXF2 reprograms breast cancer cells into bone metastasis seeds

Bone metastasis in breast cancer patients causes major skeletal-related complications. Here, the authors show that FOXF2/BMP/SMAD pathway plays a major role in bone metastasis and suggest targeting this axis to manage bone metastasis.

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Autores principales: Shuo Wang, Gui-Xi Li, Cong-Cong Tan, Rui He, Li-Juan Kang, Jun-Tao Lu, Xiao-Qing Li, Qing-Shan Wang, Pei-Fang Liu, Qiong-Li Zhai, Yu-Mei Feng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/cef0ca12bea84c3590e617cd0e94761f
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spelling oai:doaj.org-article:cef0ca12bea84c3590e617cd0e94761f2021-12-02T14:39:38ZFOXF2 reprograms breast cancer cells into bone metastasis seeds10.1038/s41467-019-10379-72041-1723https://doaj.org/article/cef0ca12bea84c3590e617cd0e94761f2019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10379-7https://doaj.org/toc/2041-1723Bone metastasis in breast cancer patients causes major skeletal-related complications. Here, the authors show that FOXF2/BMP/SMAD pathway plays a major role in bone metastasis and suggest targeting this axis to manage bone metastasis.Shuo WangGui-Xi LiCong-Cong TanRui HeLi-Juan KangJun-Tao LuXiao-Qing LiQing-Shan WangPei-Fang LiuQiong-Li ZhaiYu-Mei FengNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shuo Wang
Gui-Xi Li
Cong-Cong Tan
Rui He
Li-Juan Kang
Jun-Tao Lu
Xiao-Qing Li
Qing-Shan Wang
Pei-Fang Liu
Qiong-Li Zhai
Yu-Mei Feng
FOXF2 reprograms breast cancer cells into bone metastasis seeds
description Bone metastasis in breast cancer patients causes major skeletal-related complications. Here, the authors show that FOXF2/BMP/SMAD pathway plays a major role in bone metastasis and suggest targeting this axis to manage bone metastasis.
format article
author Shuo Wang
Gui-Xi Li
Cong-Cong Tan
Rui He
Li-Juan Kang
Jun-Tao Lu
Xiao-Qing Li
Qing-Shan Wang
Pei-Fang Liu
Qiong-Li Zhai
Yu-Mei Feng
author_facet Shuo Wang
Gui-Xi Li
Cong-Cong Tan
Rui He
Li-Juan Kang
Jun-Tao Lu
Xiao-Qing Li
Qing-Shan Wang
Pei-Fang Liu
Qiong-Li Zhai
Yu-Mei Feng
author_sort Shuo Wang
title FOXF2 reprograms breast cancer cells into bone metastasis seeds
title_short FOXF2 reprograms breast cancer cells into bone metastasis seeds
title_full FOXF2 reprograms breast cancer cells into bone metastasis seeds
title_fullStr FOXF2 reprograms breast cancer cells into bone metastasis seeds
title_full_unstemmed FOXF2 reprograms breast cancer cells into bone metastasis seeds
title_sort foxf2 reprograms breast cancer cells into bone metastasis seeds
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/cef0ca12bea84c3590e617cd0e94761f
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AT congcongtan foxf2reprogramsbreastcancercellsintobonemetastasisseeds
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