FOXF2 reprograms breast cancer cells into bone metastasis seeds
Bone metastasis in breast cancer patients causes major skeletal-related complications. Here, the authors show that FOXF2/BMP/SMAD pathway plays a major role in bone metastasis and suggest targeting this axis to manage bone metastasis.
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Nature Portfolio
2019
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oai:doaj.org-article:cef0ca12bea84c3590e617cd0e94761f2021-12-02T14:39:38ZFOXF2 reprograms breast cancer cells into bone metastasis seeds10.1038/s41467-019-10379-72041-1723https://doaj.org/article/cef0ca12bea84c3590e617cd0e94761f2019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10379-7https://doaj.org/toc/2041-1723Bone metastasis in breast cancer patients causes major skeletal-related complications. Here, the authors show that FOXF2/BMP/SMAD pathway plays a major role in bone metastasis and suggest targeting this axis to manage bone metastasis.Shuo WangGui-Xi LiCong-Cong TanRui HeLi-Juan KangJun-Tao LuXiao-Qing LiQing-Shan WangPei-Fang LiuQiong-Li ZhaiYu-Mei FengNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019) |
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Science Q Shuo Wang Gui-Xi Li Cong-Cong Tan Rui He Li-Juan Kang Jun-Tao Lu Xiao-Qing Li Qing-Shan Wang Pei-Fang Liu Qiong-Li Zhai Yu-Mei Feng FOXF2 reprograms breast cancer cells into bone metastasis seeds |
description |
Bone metastasis in breast cancer patients causes major skeletal-related complications. Here, the authors show that FOXF2/BMP/SMAD pathway plays a major role in bone metastasis and suggest targeting this axis to manage bone metastasis. |
format |
article |
author |
Shuo Wang Gui-Xi Li Cong-Cong Tan Rui He Li-Juan Kang Jun-Tao Lu Xiao-Qing Li Qing-Shan Wang Pei-Fang Liu Qiong-Li Zhai Yu-Mei Feng |
author_facet |
Shuo Wang Gui-Xi Li Cong-Cong Tan Rui He Li-Juan Kang Jun-Tao Lu Xiao-Qing Li Qing-Shan Wang Pei-Fang Liu Qiong-Li Zhai Yu-Mei Feng |
author_sort |
Shuo Wang |
title |
FOXF2 reprograms breast cancer cells into bone metastasis seeds |
title_short |
FOXF2 reprograms breast cancer cells into bone metastasis seeds |
title_full |
FOXF2 reprograms breast cancer cells into bone metastasis seeds |
title_fullStr |
FOXF2 reprograms breast cancer cells into bone metastasis seeds |
title_full_unstemmed |
FOXF2 reprograms breast cancer cells into bone metastasis seeds |
title_sort |
foxf2 reprograms breast cancer cells into bone metastasis seeds |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/cef0ca12bea84c3590e617cd0e94761f |
work_keys_str_mv |
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