FOXF2 reprograms breast cancer cells into bone metastasis seeds

Bone metastasis in breast cancer patients causes major skeletal-related complications. Here, the authors show that FOXF2/BMP/SMAD pathway plays a major role in bone metastasis and suggest targeting this axis to manage bone metastasis.

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Bibliographic Details
Main Authors: Shuo Wang, Gui-Xi Li, Cong-Cong Tan, Rui He, Li-Juan Kang, Jun-Tao Lu, Xiao-Qing Li, Qing-Shan Wang, Pei-Fang Liu, Qiong-Li Zhai, Yu-Mei Feng
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/cef0ca12bea84c3590e617cd0e94761f
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