Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate
In the Drosophila ovary, it is unclear how signalling from the stem cell niche regulates follicle precursor cell fate/differentiation. Here, the authors use quantitative microscopy to define the role of Wnt, Hedgehog and Notch signalling in progenitor cells, showing regulation of cell fate and diffe...
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Nature Portfolio
2017
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oai:doaj.org-article:cef3547af0f747c5ab889b4bac57c60f2021-12-02T14:41:59ZQuantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate10.1038/s41467-017-01322-92041-1723https://doaj.org/article/cef3547af0f747c5ab889b4bac57c60f2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01322-9https://doaj.org/toc/2041-1723In the Drosophila ovary, it is unclear how signalling from the stem cell niche regulates follicle precursor cell fate/differentiation. Here, the authors use quantitative microscopy to define the role of Wnt, Hedgehog and Notch signalling in progenitor cells, showing regulation of cell fate and differentiation.Wei DaiAmy PetersonThomas KenneyHaley BurrousDenise J. MontellNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017) |
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Science Q Wei Dai Amy Peterson Thomas Kenney Haley Burrous Denise J. Montell Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate |
description |
In the Drosophila ovary, it is unclear how signalling from the stem cell niche regulates follicle precursor cell fate/differentiation. Here, the authors use quantitative microscopy to define the role of Wnt, Hedgehog and Notch signalling in progenitor cells, showing regulation of cell fate and differentiation. |
format |
article |
author |
Wei Dai Amy Peterson Thomas Kenney Haley Burrous Denise J. Montell |
author_facet |
Wei Dai Amy Peterson Thomas Kenney Haley Burrous Denise J. Montell |
author_sort |
Wei Dai |
title |
Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate |
title_short |
Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate |
title_full |
Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate |
title_fullStr |
Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate |
title_full_unstemmed |
Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate |
title_sort |
quantitative microscopy of the drosophila ovary shows multiple niche signals specify progenitor cell fate |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/cef3547af0f747c5ab889b4bac57c60f |
work_keys_str_mv |
AT weidai quantitativemicroscopyofthedrosophilaovaryshowsmultiplenichesignalsspecifyprogenitorcellfate AT amypeterson quantitativemicroscopyofthedrosophilaovaryshowsmultiplenichesignalsspecifyprogenitorcellfate AT thomaskenney quantitativemicroscopyofthedrosophilaovaryshowsmultiplenichesignalsspecifyprogenitorcellfate AT haleyburrous quantitativemicroscopyofthedrosophilaovaryshowsmultiplenichesignalsspecifyprogenitorcellfate AT denisejmontell quantitativemicroscopyofthedrosophilaovaryshowsmultiplenichesignalsspecifyprogenitorcellfate |
_version_ |
1718389837569982464 |