Fh15 Blocks the Lipopolysaccharide-Induced Cytokine Storm While Modulating Peritoneal Macrophage Migration and CD38 Expression within Spleen Macrophages in a Mouse Model of Septic Shock
ABSTRACT Sepsis caused by Gram-negative bacteria is the consequence of an unrestrained infection that continuously releases lipopolysaccharide (LPS) into the bloodstream, which triggers an uncontrolled systemic inflammatory response leading to multiorgan failure and death. After scrutinizing the imm...
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Main Authors: | Marcos J. Ramos-Benitez, Caleb Ruiz-Jimenez, Jose J. Rosado-Franco, Willy D. Ramos-Pérez, Loyda B. Mendez, Antonio Osuna, Ana M. Espino |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2018
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Online Access: | https://doaj.org/article/cef3d064ad834faaac6cd5b629a2ab13 |
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