Target-dependent biogenesis of cognate microRNAs in human cells
MicroRNAs are a widespread regulatory mechanism and are themselves extensively regulated. Here the authors show regulated miRNA biogenesis by the target mRNA, a layer of regulation that modulates miRNA levels dependent on target availability.
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Nature Portfolio
2016
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oai:doaj.org-article:cef5727f11e84df894917c0dd0506e672021-12-02T15:35:19ZTarget-dependent biogenesis of cognate microRNAs in human cells10.1038/ncomms122002041-1723https://doaj.org/article/cef5727f11e84df894917c0dd0506e672016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms12200https://doaj.org/toc/2041-1723MicroRNAs are a widespread regulatory mechanism and are themselves extensively regulated. Here the authors show regulated miRNA biogenesis by the target mRNA, a layer of regulation that modulates miRNA levels dependent on target availability.Mainak BoseSuvendra N. BhattacharyyaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016) |
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Science Q Mainak Bose Suvendra N. Bhattacharyya Target-dependent biogenesis of cognate microRNAs in human cells |
description |
MicroRNAs are a widespread regulatory mechanism and are themselves extensively regulated. Here the authors show regulated miRNA biogenesis by the target mRNA, a layer of regulation that modulates miRNA levels dependent on target availability. |
format |
article |
author |
Mainak Bose Suvendra N. Bhattacharyya |
author_facet |
Mainak Bose Suvendra N. Bhattacharyya |
author_sort |
Mainak Bose |
title |
Target-dependent biogenesis of cognate microRNAs in human cells |
title_short |
Target-dependent biogenesis of cognate microRNAs in human cells |
title_full |
Target-dependent biogenesis of cognate microRNAs in human cells |
title_fullStr |
Target-dependent biogenesis of cognate microRNAs in human cells |
title_full_unstemmed |
Target-dependent biogenesis of cognate microRNAs in human cells |
title_sort |
target-dependent biogenesis of cognate micrornas in human cells |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/cef5727f11e84df894917c0dd0506e67 |
work_keys_str_mv |
AT mainakbose targetdependentbiogenesisofcognatemicrornasinhumancells AT suvendranbhattacharyya targetdependentbiogenesisofcognatemicrornasinhumancells |
_version_ |
1718386624803373056 |