Nanomechanics and co-transcriptional folding of Spinach and Mango

Light-up aptamers are widely used for fluorescence visualization of non-coding RNA in vivo. Here the authors employ single-molecule fluorescence-force spectroscopy to characterize the mechanical responses of the G-Quadruplex based light-up aptamers Spinach2, iMangoIII and MangoIV, which is of intere...

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Autores principales:	Jaba Mitra, Taekjip Ha
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/cefd0b4291b14d72bec544539ac8e247
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spelling	oai:doaj.org-article:cefd0b4291b14d72bec544539ac8e2472021-12-02T17:02:11ZNanomechanics and co-transcriptional folding of Spinach and Mango10.1038/s41467-019-12299-y2041-1723https://doaj.org/article/cefd0b4291b14d72bec544539ac8e2472019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12299-yhttps://doaj.org/toc/2041-1723Light-up aptamers are widely used for fluorescence visualization of non-coding RNA in vivo. Here the authors employ single-molecule fluorescence-force spectroscopy to characterize the mechanical responses of the G-Quadruplex based light-up aptamers Spinach2, iMangoIII and MangoIV, which is of interest for the development of improved fluorogenic modules for imaging applications.Jaba MitraTaekjip HaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jaba Mitra Taekjip Ha Nanomechanics and co-transcriptional folding of Spinach and Mango
description	Light-up aptamers are widely used for fluorescence visualization of non-coding RNA in vivo. Here the authors employ single-molecule fluorescence-force spectroscopy to characterize the mechanical responses of the G-Quadruplex based light-up aptamers Spinach2, iMangoIII and MangoIV, which is of interest for the development of improved fluorogenic modules for imaging applications.
format	article
author	Jaba Mitra Taekjip Ha
author_facet	Jaba Mitra Taekjip Ha
author_sort	Jaba Mitra
title	Nanomechanics and co-transcriptional folding of Spinach and Mango
title_short	Nanomechanics and co-transcriptional folding of Spinach and Mango
title_full	Nanomechanics and co-transcriptional folding of Spinach and Mango
title_fullStr	Nanomechanics and co-transcriptional folding of Spinach and Mango
title_full_unstemmed	Nanomechanics and co-transcriptional folding of Spinach and Mango
title_sort	nanomechanics and co-transcriptional folding of spinach and mango
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/cefd0b4291b14d72bec544539ac8e247
work_keys_str_mv	AT jabamitra nanomechanicsandcotranscriptionalfoldingofspinachandmango AT taekjipha nanomechanicsandcotranscriptionalfoldingofspinachandmango
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Nanomechanics and co-transcriptional folding of Spinach and Mango

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