Nanomechanics and co-transcriptional folding of Spinach and Mango

Light-up aptamers are widely used for fluorescence visualization of non-coding RNA in vivo. Here the authors employ single-molecule fluorescence-force spectroscopy to characterize the mechanical responses of the G-Quadruplex based light-up aptamers Spinach2, iMangoIII and MangoIV, which is of intere...

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Auteurs principaux: Jaba Mitra, Taekjip Ha
Format: article
Langue:EN
Publié: Nature Portfolio 2019
Sujets:
Q
Accès en ligne:https://doaj.org/article/cefd0b4291b14d72bec544539ac8e247
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