Quantitative Morphology as a Prognostic Factor in Feline Spontaneous Cutaneous Squamous Cell Carcinomas

In a study on cytological specimens from 30 cats with histologically confi rmed cutaneous squamous cell carcinoma, the morphometric variables mean nuclear area (MNA, μm2), mean nuclear perimeter (MNP, μm), mean nuclear diameter (D mean, μm), minimum nuclear diameter (D min, μm) and maximum nuclear d...

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Autor principal:	Radostina Simeonov
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2018
Materias:	nuclear morphometry feline cutaneous squamous cell carcinomas metastases prognosis Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/cf0198f3b3a84642a39252961645c48a
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spelling	oai:doaj.org-article:cf0198f3b3a84642a39252961645c48a2021-11-17T21:27:52ZQuantitative Morphology as a Prognostic Factor in Feline Spontaneous Cutaneous Squamous Cell Carcinomas1820-744810.2478/acve-2018-0022https://doaj.org/article/cf0198f3b3a84642a39252961645c48a2018-09-01T00:00:00Zhttps://doi.org/10.2478/acve-2018-0022https://doaj.org/toc/1820-7448In a study on cytological specimens from 30 cats with histologically confi rmed cutaneous squamous cell carcinoma, the morphometric variables mean nuclear area (MNA, μm2), mean nuclear perimeter (MNP, μm), mean nuclear diameter (D mean, μm), minimum nuclear diameter (D min, μm) and maximum nuclear diameter (D max, μm) were studied and compared to metastases in regional lymph nodes. The mean values of these parameters were signifi cantly greater in cats with lymph node metastases compared to parameters of tumour cells from cats which were lymph node-negative. A signifi cant positive correlation was observed between all studied morphometric parameters and metastases in the regional lymph nodes. In conclusion, computer -assisted nuclear morphometry could be used as a prognostic method in the diagnosis of spontaneous feline cutaneous squamous cell carcinomas.Radostina SimeonovSciendoarticlenuclear morphometryfeline cutaneous squamous cell carcinomasmetastasesprognosisVeterinary medicineSF600-1100ENActa Veterinaria, Vol 68, Iss 3, Pp 251-256 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	nuclear morphometry feline cutaneous squamous cell carcinomas metastases prognosis Veterinary medicine SF600-1100
spellingShingle	nuclear morphometry feline cutaneous squamous cell carcinomas metastases prognosis Veterinary medicine SF600-1100 Radostina Simeonov Quantitative Morphology as a Prognostic Factor in Feline Spontaneous Cutaneous Squamous Cell Carcinomas
description	In a study on cytological specimens from 30 cats with histologically confi rmed cutaneous squamous cell carcinoma, the morphometric variables mean nuclear area (MNA, μm2), mean nuclear perimeter (MNP, μm), mean nuclear diameter (D mean, μm), minimum nuclear diameter (D min, μm) and maximum nuclear diameter (D max, μm) were studied and compared to metastases in regional lymph nodes. The mean values of these parameters were signifi cantly greater in cats with lymph node metastases compared to parameters of tumour cells from cats which were lymph node-negative. A signifi cant positive correlation was observed between all studied morphometric parameters and metastases in the regional lymph nodes. In conclusion, computer -assisted nuclear morphometry could be used as a prognostic method in the diagnosis of spontaneous feline cutaneous squamous cell carcinomas.
format	article
author	Radostina Simeonov
author_facet	Radostina Simeonov
author_sort	Radostina Simeonov
title	Quantitative Morphology as a Prognostic Factor in Feline Spontaneous Cutaneous Squamous Cell Carcinomas
title_short	Quantitative Morphology as a Prognostic Factor in Feline Spontaneous Cutaneous Squamous Cell Carcinomas
title_full	Quantitative Morphology as a Prognostic Factor in Feline Spontaneous Cutaneous Squamous Cell Carcinomas
title_fullStr	Quantitative Morphology as a Prognostic Factor in Feline Spontaneous Cutaneous Squamous Cell Carcinomas
title_full_unstemmed	Quantitative Morphology as a Prognostic Factor in Feline Spontaneous Cutaneous Squamous Cell Carcinomas
title_sort	quantitative morphology as a prognostic factor in feline spontaneous cutaneous squamous cell carcinomas
publisher	Sciendo
publishDate	2018
url	https://doaj.org/article/cf0198f3b3a84642a39252961645c48a
work_keys_str_mv	AT radostinasimeonov quantitativemorphologyasaprognosticfactorinfelinespontaneouscutaneoussquamouscellcarcinomas
_version_	1718425318361923584

Quantitative Morphology as a Prognostic Factor in Feline Spontaneous Cutaneous Squamous Cell Carcinomas

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