Global epigenetic regulation of microRNAs in multiple myeloma.

Global epigenetic regulation of microRNAs in multiple myeloma.

Epigenetic changes frequently occur during tumorigenesis and DNA hypermethylation may account for the inactivation of tumor suppressor genes in cancer cells. Studies in Multiple Myeloma (MM) have shown variable DNA methylation patterns with focal hypermethylation changes in clinically aggressive sub...

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Bibliographic Details
Main Authors: Wenjing Zhang, Yaoyu E Wang, Yu Zhang, Xavier Leleu, Michaela Reagan, Yong Zhang, Yuji Mishima, Siobhan Glavey, Salomon Manier, Antonio Sacco, Bo Jiang, Aldo M Roccaro, Irene M Ghobrial
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/cf08cdb52ee0441a9a83c818eadb3a8d
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