Neurocognitive Manifestations of SARS-CoV2: A Narrative Review of Mechanisms

Since the outbreak of COVID-19 that is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2020 throughout the world, a lot of aspects of people’s lives are affected including their psychological status. Follow-up assessment of survivors of this infection showed that they had m...

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Autores principales:	Mahrooz Roozbeh, Mehrdad Roozbeh, Hossein Pakdaman, Seyed Ali Sobhanian, Amin Edalatkhah, Saeid Safari
Formato:	article
Lenguaje:	EN
Publicado:	Shahid Beheshti University of Medical Sciences 2020
Materias:	covid-19 cognitive dysfunction anxiety depression delirium inflammation hypoxia Medicine R
Acceso en línea:	https://doaj.org/article/cf16b86c3345463baccbf1f5642cf5c1
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spelling	oai:doaj.org-article:cf16b86c3345463baccbf1f5642cf5c12021-11-16T10:50:32ZNeurocognitive Manifestations of SARS-CoV2: A Narrative Review of Mechanisms2383-18712383-209610.34172/icnj.2021.02https://doaj.org/article/cf16b86c3345463baccbf1f5642cf5c12020-12-01T00:00:00Zhttps://journals.sbmu.ac.ir/neuroscience/article/view/32993/26383https://doaj.org/toc/2383-1871https://doaj.org/toc/2383-2096Since the outbreak of COVID-19 that is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2020 throughout the world, a lot of aspects of people’s lives are affected including their psychological status. Follow-up assessment of survivors of this infection showed that they had multiple psychological disorders including depression, panic attacks, obsessive compulsive disorder, and post-traumatic stress disorder. It is estimated that more than one-third of patients with COVID-19 experience neuropsychiatric symptoms, including headache, paresthesia, and disturbed consciousness. Among patients affected by COVID-19, there are different mechanisms that can cause cognitive dysfunction. COVID-19 can affect the central nervous system (CNS) directly by invasion and indirectly by inducing hypoxia, inflammation, and delirium. The pandemic and fear of infection can also cause anxiety which impairs the cognition as well. By assessing the patients’ cognition and knowing the higher probable cause of cognitive impairment, we can form a better strategy to better treat the impairment. Cognitive behavioral therapy can be effective in reducing the anxiety and cognitive rehabilitation therapy (CRT) can be used to lower the detrimental effects of cognitive impairment caused by COVID-19.Mahrooz RoozbehMehrdad RoozbehHossein PakdamanSeyed Ali SobhanianAmin EdalatkhahSaeid SafariShahid Beheshti University of Medical Sciencesarticlecovid-19cognitive dysfunctionanxietydepressiondeliriuminflammationhypoxiaMedicineRENInternational Clinical Neuroscience Journal, Vol 8, Iss 1, Pp 3-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	covid-19 cognitive dysfunction anxiety depression delirium inflammation hypoxia Medicine R
spellingShingle	covid-19 cognitive dysfunction anxiety depression delirium inflammation hypoxia Medicine R Mahrooz Roozbeh Mehrdad Roozbeh Hossein Pakdaman Seyed Ali Sobhanian Amin Edalatkhah Saeid Safari Neurocognitive Manifestations of SARS-CoV2: A Narrative Review of Mechanisms
description	Since the outbreak of COVID-19 that is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2020 throughout the world, a lot of aspects of people’s lives are affected including their psychological status. Follow-up assessment of survivors of this infection showed that they had multiple psychological disorders including depression, panic attacks, obsessive compulsive disorder, and post-traumatic stress disorder. It is estimated that more than one-third of patients with COVID-19 experience neuropsychiatric symptoms, including headache, paresthesia, and disturbed consciousness. Among patients affected by COVID-19, there are different mechanisms that can cause cognitive dysfunction. COVID-19 can affect the central nervous system (CNS) directly by invasion and indirectly by inducing hypoxia, inflammation, and delirium. The pandemic and fear of infection can also cause anxiety which impairs the cognition as well. By assessing the patients’ cognition and knowing the higher probable cause of cognitive impairment, we can form a better strategy to better treat the impairment. Cognitive behavioral therapy can be effective in reducing the anxiety and cognitive rehabilitation therapy (CRT) can be used to lower the detrimental effects of cognitive impairment caused by COVID-19.
format	article
author	Mahrooz Roozbeh Mehrdad Roozbeh Hossein Pakdaman Seyed Ali Sobhanian Amin Edalatkhah Saeid Safari
author_facet	Mahrooz Roozbeh Mehrdad Roozbeh Hossein Pakdaman Seyed Ali Sobhanian Amin Edalatkhah Saeid Safari
author_sort	Mahrooz Roozbeh
title	Neurocognitive Manifestations of SARS-CoV2: A Narrative Review of Mechanisms
title_short	Neurocognitive Manifestations of SARS-CoV2: A Narrative Review of Mechanisms
title_full	Neurocognitive Manifestations of SARS-CoV2: A Narrative Review of Mechanisms
title_fullStr	Neurocognitive Manifestations of SARS-CoV2: A Narrative Review of Mechanisms
title_full_unstemmed	Neurocognitive Manifestations of SARS-CoV2: A Narrative Review of Mechanisms
title_sort	neurocognitive manifestations of sars-cov2: a narrative review of mechanisms
publisher	Shahid Beheshti University of Medical Sciences
publishDate	2020
url	https://doaj.org/article/cf16b86c3345463baccbf1f5642cf5c1
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Neurocognitive Manifestations of SARS-CoV2: A Narrative Review of Mechanisms

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