Grasp55 −/− mice display impaired fat absorption and resistance to high-fat diet-induced obesity

The physiological roles of the Golgi reassembly-stacking protein 55 (GRASP55/GORASP55) remain largely elusive. Here, the authors show that the Golgi-resident protein GRASP55 plays a crucial role in lipid homeostasis by regulating intestinal lipid uptake.

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Autores principales: Jiyoon Kim, Hyeyon Kim, Shin Hye Noh, Dong Geon Jang, Shi-Young Park, Dongkook Min, Hyunki Kim, Hee-Seok Kweon, Hoguen Kim, Sowon Aum, Sookyung Seo, Cheol Soo Choi, Hail Kim, Jae Woo Kim, Seok Jun Moon, Heon Yung Gee, Min Goo Lee
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/cf1efe464e0048bcb1c2c89a7f1a6032
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spelling oai:doaj.org-article:cf1efe464e0048bcb1c2c89a7f1a60322021-12-02T14:40:52ZGrasp55 −/− mice display impaired fat absorption and resistance to high-fat diet-induced obesity10.1038/s41467-020-14912-x2041-1723https://doaj.org/article/cf1efe464e0048bcb1c2c89a7f1a60322020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14912-xhttps://doaj.org/toc/2041-1723The physiological roles of the Golgi reassembly-stacking protein 55 (GRASP55/GORASP55) remain largely elusive. Here, the authors show that the Golgi-resident protein GRASP55 plays a crucial role in lipid homeostasis by regulating intestinal lipid uptake.Jiyoon KimHyeyon KimShin Hye NohDong Geon JangShi-Young ParkDongkook MinHyunki KimHee-Seok KweonHoguen KimSowon AumSookyung SeoCheol Soo ChoiHail KimJae Woo KimSeok Jun MoonHeon Yung GeeMin Goo LeeNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jiyoon Kim
Hyeyon Kim
Shin Hye Noh
Dong Geon Jang
Shi-Young Park
Dongkook Min
Hyunki Kim
Hee-Seok Kweon
Hoguen Kim
Sowon Aum
Sookyung Seo
Cheol Soo Choi
Hail Kim
Jae Woo Kim
Seok Jun Moon
Heon Yung Gee
Min Goo Lee
Grasp55 −/− mice display impaired fat absorption and resistance to high-fat diet-induced obesity
description The physiological roles of the Golgi reassembly-stacking protein 55 (GRASP55/GORASP55) remain largely elusive. Here, the authors show that the Golgi-resident protein GRASP55 plays a crucial role in lipid homeostasis by regulating intestinal lipid uptake.
format article
author Jiyoon Kim
Hyeyon Kim
Shin Hye Noh
Dong Geon Jang
Shi-Young Park
Dongkook Min
Hyunki Kim
Hee-Seok Kweon
Hoguen Kim
Sowon Aum
Sookyung Seo
Cheol Soo Choi
Hail Kim
Jae Woo Kim
Seok Jun Moon
Heon Yung Gee
Min Goo Lee
author_facet Jiyoon Kim
Hyeyon Kim
Shin Hye Noh
Dong Geon Jang
Shi-Young Park
Dongkook Min
Hyunki Kim
Hee-Seok Kweon
Hoguen Kim
Sowon Aum
Sookyung Seo
Cheol Soo Choi
Hail Kim
Jae Woo Kim
Seok Jun Moon
Heon Yung Gee
Min Goo Lee
author_sort Jiyoon Kim
title Grasp55 −/− mice display impaired fat absorption and resistance to high-fat diet-induced obesity
title_short Grasp55 −/− mice display impaired fat absorption and resistance to high-fat diet-induced obesity
title_full Grasp55 −/− mice display impaired fat absorption and resistance to high-fat diet-induced obesity
title_fullStr Grasp55 −/− mice display impaired fat absorption and resistance to high-fat diet-induced obesity
title_full_unstemmed Grasp55 −/− mice display impaired fat absorption and resistance to high-fat diet-induced obesity
title_sort grasp55 −/− mice display impaired fat absorption and resistance to high-fat diet-induced obesity
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/cf1efe464e0048bcb1c2c89a7f1a6032
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