Fungal Endophthalmitis: A Comprehensive Review

Endophthalmitis is a serious ophthalmologic condition involving purulent inflammation of the intraocular spaces. The underlying etiology of infectious endophthalmitis is typically bacterial or fungal. The mechanism of entry into the eye is either exogenous, involving seeding of an infectious source...

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Autores principales:	Abid A. Haseeb, Abdelrahman M. Elhusseiny, Mohammad Z. Siddiqui, Kinza T. Ahmad, Ahmed B. Sallam
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	fungal endophthalmitis exogenous endophthalmitis endogenous endophthalmitis <i>Candida</i> <i>Aspergillus</i> antifungals Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/cf2344f4b9de44bd813e8fbb3df9ed97
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spelling	oai:doaj.org-article:cf2344f4b9de44bd813e8fbb3df9ed972021-11-25T18:06:39ZFungal Endophthalmitis: A Comprehensive Review10.3390/jof71109962309-608Xhttps://doaj.org/article/cf2344f4b9de44bd813e8fbb3df9ed972021-11-01T00:00:00Zhttps://www.mdpi.com/2309-608X/7/11/996https://doaj.org/toc/2309-608XEndophthalmitis is a serious ophthalmologic condition involving purulent inflammation of the intraocular spaces. The underlying etiology of infectious endophthalmitis is typically bacterial or fungal. The mechanism of entry into the eye is either exogenous, involving seeding of an infectious source from outside the eye (e.g., trauma or surgical complications), or endogenous, involving transit of an infectious source to the eye via the bloodstream. The most common organism for fungal endophthalmitis is <i>Candida albicans.</i> The most common clinical manifestation of fungal endophthalmitis is vision loss, but other signs of inflammation and infection are frequently present. Fungal endophthalmitis is a clinical diagnosis, which can be supported by vitreous, aqueous, or blood cultures. Treatment involves systemic and intravitreal antifungal medications as well as possible pars plana vitrectomy. In this review, we examine these essential elements of understanding fungal endophthalmitis as a clinically relevant entity, which threatens patients’ vision.Abid A. HaseebAbdelrahman M. ElhusseinyMohammad Z. SiddiquiKinza T. AhmadAhmed B. SallamMDPI AGarticlefungal endophthalmitisexogenous endophthalmitisendogenous endophthalmitis<i>Candida</i><i>Aspergillus</i>antifungalsBiology (General)QH301-705.5ENJournal of Fungi, Vol 7, Iss 996, p 996 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	fungal endophthalmitis exogenous endophthalmitis endogenous endophthalmitis <i>Candida</i> <i>Aspergillus</i> antifungals Biology (General) QH301-705.5
spellingShingle	fungal endophthalmitis exogenous endophthalmitis endogenous endophthalmitis <i>Candida</i> <i>Aspergillus</i> antifungals Biology (General) QH301-705.5 Abid A. Haseeb Abdelrahman M. Elhusseiny Mohammad Z. Siddiqui Kinza T. Ahmad Ahmed B. Sallam Fungal Endophthalmitis: A Comprehensive Review
description	Endophthalmitis is a serious ophthalmologic condition involving purulent inflammation of the intraocular spaces. The underlying etiology of infectious endophthalmitis is typically bacterial or fungal. The mechanism of entry into the eye is either exogenous, involving seeding of an infectious source from outside the eye (e.g., trauma or surgical complications), or endogenous, involving transit of an infectious source to the eye via the bloodstream. The most common organism for fungal endophthalmitis is <i>Candida albicans.</i> The most common clinical manifestation of fungal endophthalmitis is vision loss, but other signs of inflammation and infection are frequently present. Fungal endophthalmitis is a clinical diagnosis, which can be supported by vitreous, aqueous, or blood cultures. Treatment involves systemic and intravitreal antifungal medications as well as possible pars plana vitrectomy. In this review, we examine these essential elements of understanding fungal endophthalmitis as a clinically relevant entity, which threatens patients’ vision.
format	article
author	Abid A. Haseeb Abdelrahman M. Elhusseiny Mohammad Z. Siddiqui Kinza T. Ahmad Ahmed B. Sallam
author_facet	Abid A. Haseeb Abdelrahman M. Elhusseiny Mohammad Z. Siddiqui Kinza T. Ahmad Ahmed B. Sallam
author_sort	Abid A. Haseeb
title	Fungal Endophthalmitis: A Comprehensive Review
title_short	Fungal Endophthalmitis: A Comprehensive Review
title_full	Fungal Endophthalmitis: A Comprehensive Review
title_fullStr	Fungal Endophthalmitis: A Comprehensive Review
title_full_unstemmed	Fungal Endophthalmitis: A Comprehensive Review
title_sort	fungal endophthalmitis: a comprehensive review
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/cf2344f4b9de44bd813e8fbb3df9ed97
work_keys_str_mv	AT abidahaseeb fungalendophthalmitisacomprehensivereview AT abdelrahmanmelhusseiny fungalendophthalmitisacomprehensivereview AT mohammadzsiddiqui fungalendophthalmitisacomprehensivereview AT kinzatahmad fungalendophthalmitisacomprehensivereview AT ahmedbsallam fungalendophthalmitisacomprehensivereview
_version_	1718411645222387712

Fungal Endophthalmitis: A Comprehensive Review

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