Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy
While nanocarrier-based drug delivery is a promising therapeutic approach, in situ characterization of drug nanocarriers in blood remains difficult. Here, the authors demonstrate how the fluorescence correlation spectroscopy can be used to directly characterize drug nanocarriers in flowing blood.
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Nature Portfolio
2018
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oai:doaj.org-article:cf29261ca73b441fab35b8f08719a6592021-12-02T14:39:43ZMonitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy10.1038/s41467-018-07755-02041-1723https://doaj.org/article/cf29261ca73b441fab35b8f08719a6592018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07755-0https://doaj.org/toc/2041-1723While nanocarrier-based drug delivery is a promising therapeutic approach, in situ characterization of drug nanocarriers in blood remains difficult. Here, the authors demonstrate how the fluorescence correlation spectroscopy can be used to directly characterize drug nanocarriers in flowing blood.Inka NegwerAndreas BestMeike SchinnererOlga SchäferLeon CapeloaManfred WagnerManfred SchmidtVolker MailänderMark HelmMatthias BarzHans-Jürgen ButtKaloian KoynovNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018) |
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Science Q Inka Negwer Andreas Best Meike Schinnerer Olga Schäfer Leon Capeloa Manfred Wagner Manfred Schmidt Volker Mailänder Mark Helm Matthias Barz Hans-Jürgen Butt Kaloian Koynov Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy |
description |
While nanocarrier-based drug delivery is a promising therapeutic approach, in situ characterization of drug nanocarriers in blood remains difficult. Here, the authors demonstrate how the fluorescence correlation spectroscopy can be used to directly characterize drug nanocarriers in flowing blood. |
format |
article |
author |
Inka Negwer Andreas Best Meike Schinnerer Olga Schäfer Leon Capeloa Manfred Wagner Manfred Schmidt Volker Mailänder Mark Helm Matthias Barz Hans-Jürgen Butt Kaloian Koynov |
author_facet |
Inka Negwer Andreas Best Meike Schinnerer Olga Schäfer Leon Capeloa Manfred Wagner Manfred Schmidt Volker Mailänder Mark Helm Matthias Barz Hans-Jürgen Butt Kaloian Koynov |
author_sort |
Inka Negwer |
title |
Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy |
title_short |
Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy |
title_full |
Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy |
title_fullStr |
Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy |
title_full_unstemmed |
Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy |
title_sort |
monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/cf29261ca73b441fab35b8f08719a659 |
work_keys_str_mv |
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_version_ |
1718390560002146304 |