Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy

While nanocarrier-based drug delivery is a promising therapeutic approach, in situ characterization of drug nanocarriers in blood remains difficult. Here, the authors demonstrate how the fluorescence correlation spectroscopy can be used to directly characterize drug nanocarriers in flowing blood.

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Autores principales: Inka Negwer, Andreas Best, Meike Schinnerer, Olga Schäfer, Leon Capeloa, Manfred Wagner, Manfred Schmidt, Volker Mailänder, Mark Helm, Matthias Barz, Hans-Jürgen Butt, Kaloian Koynov
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/cf29261ca73b441fab35b8f08719a659
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spelling oai:doaj.org-article:cf29261ca73b441fab35b8f08719a6592021-12-02T14:39:43ZMonitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy10.1038/s41467-018-07755-02041-1723https://doaj.org/article/cf29261ca73b441fab35b8f08719a6592018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07755-0https://doaj.org/toc/2041-1723While nanocarrier-based drug delivery is a promising therapeutic approach, in situ characterization of drug nanocarriers in blood remains difficult. Here, the authors demonstrate how the fluorescence correlation spectroscopy can be used to directly characterize drug nanocarriers in flowing blood.Inka NegwerAndreas BestMeike SchinnererOlga SchäferLeon CapeloaManfred WagnerManfred SchmidtVolker MailänderMark HelmMatthias BarzHans-Jürgen ButtKaloian KoynovNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Inka Negwer
Andreas Best
Meike Schinnerer
Olga Schäfer
Leon Capeloa
Manfred Wagner
Manfred Schmidt
Volker Mailänder
Mark Helm
Matthias Barz
Hans-Jürgen Butt
Kaloian Koynov
Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy
description While nanocarrier-based drug delivery is a promising therapeutic approach, in situ characterization of drug nanocarriers in blood remains difficult. Here, the authors demonstrate how the fluorescence correlation spectroscopy can be used to directly characterize drug nanocarriers in flowing blood.
format article
author Inka Negwer
Andreas Best
Meike Schinnerer
Olga Schäfer
Leon Capeloa
Manfred Wagner
Manfred Schmidt
Volker Mailänder
Mark Helm
Matthias Barz
Hans-Jürgen Butt
Kaloian Koynov
author_facet Inka Negwer
Andreas Best
Meike Schinnerer
Olga Schäfer
Leon Capeloa
Manfred Wagner
Manfred Schmidt
Volker Mailänder
Mark Helm
Matthias Barz
Hans-Jürgen Butt
Kaloian Koynov
author_sort Inka Negwer
title Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy
title_short Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy
title_full Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy
title_fullStr Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy
title_full_unstemmed Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy
title_sort monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/cf29261ca73b441fab35b8f08719a659
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