Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction

Niemöller et al. describe a bisulfite-free assay to assess epigenomics and genomics of single cells (epi-gSCAR). epi-gSCAR generates accurate and reproducible measurements of global DNA methylation and genetic variants at the single cell level, allowing for in-depth analyses of cell-to-cell heteroge...

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Autores principales:	Christoph Niemöller, Julius Wehrle, Julian Riba, Rainer Claus, Nathalie Renz, Janika Rhein, Sabine Bleul, Juliane M. Stosch, Justus Duyster, Christoph Plass, Pavlo Lutsik, Daniel B. Lipka, Michael Lübbert, Heiko Becker
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/cf2fb844146243e2a468922f8c181aef
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spelling	oai:doaj.org-article:cf2fb844146243e2a468922f8c181aef2021-12-02T10:44:14ZBisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction10.1038/s42003-021-01661-w2399-3642https://doaj.org/article/cf2fb844146243e2a468922f8c181aef2021-02-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01661-whttps://doaj.org/toc/2399-3642Niemöller et al. describe a bisulfite-free assay to assess epigenomics and genomics of single cells (epi-gSCAR). epi-gSCAR generates accurate and reproducible measurements of global DNA methylation and genetic variants at the single cell level, allowing for in-depth analyses of cell-to-cell heterogeneity.Christoph NiemöllerJulius WehrleJulian RibaRainer ClausNathalie RenzJanika RheinSabine BleulJuliane M. StoschJustus DuysterChristoph PlassPavlo LutsikDaniel B. LipkaMichael LübbertHeiko BeckerNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Christoph Niemöller Julius Wehrle Julian Riba Rainer Claus Nathalie Renz Janika Rhein Sabine Bleul Juliane M. Stosch Justus Duyster Christoph Plass Pavlo Lutsik Daniel B. Lipka Michael Lübbert Heiko Becker Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction
description	Niemöller et al. describe a bisulfite-free assay to assess epigenomics and genomics of single cells (epi-gSCAR). epi-gSCAR generates accurate and reproducible measurements of global DNA methylation and genetic variants at the single cell level, allowing for in-depth analyses of cell-to-cell heterogeneity.
format	article
author	Christoph Niemöller Julius Wehrle Julian Riba Rainer Claus Nathalie Renz Janika Rhein Sabine Bleul Juliane M. Stosch Justus Duyster Christoph Plass Pavlo Lutsik Daniel B. Lipka Michael Lübbert Heiko Becker
author_facet	Christoph Niemöller Julius Wehrle Julian Riba Rainer Claus Nathalie Renz Janika Rhein Sabine Bleul Juliane M. Stosch Justus Duyster Christoph Plass Pavlo Lutsik Daniel B. Lipka Michael Lübbert Heiko Becker
author_sort	Christoph Niemöller
title	Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction
title_short	Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction
title_full	Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction
title_fullStr	Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction
title_full_unstemmed	Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction
title_sort	bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/cf2fb844146243e2a468922f8c181aef
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Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction

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