Linking splicing to Pol II transcription stabilizes pre-mRNAs and influences splicing patterns.

RNA processing is carried out in close proximity to the site of transcription, suggesting a regulatory link between transcription and pre-mRNA splicing. Using an in vitro transcription/splicing assay, we demonstrate that an association of RNA polymerase II (Pol II) transcription and pre-mRNA splicin...

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Bibliographic Details
Main Authors: Martin J Hicks, Chin-Rang Yang, Matthew V Kotlajich, Klemens J Hertel
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2006
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Online Access:https://doaj.org/article/cf3042a3e34a4732ba67adaac8d51c96
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