Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues

Cardiomyocytes derived from human induced pluripotent stem cells could be used to generate cardiac tissues for regenerative purposes. Here the authors describe a method to obtain large bioengineered heart tissues showing advanced maturation, functional features and engraftment capacity.

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Autores principales: Ilya Y. Shadrin, Brian W. Allen, Ying Qian, Christopher P. Jackman, Aaron L. Carlson, Mark E. Juhas, Nenad Bursac
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/cf30a3c33e6d47d2acb195744c55d771
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spelling oai:doaj.org-article:cf30a3c33e6d47d2acb195744c55d7712021-12-02T14:40:59ZCardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues10.1038/s41467-017-01946-x2041-1723https://doaj.org/article/cf30a3c33e6d47d2acb195744c55d7712017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01946-xhttps://doaj.org/toc/2041-1723Cardiomyocytes derived from human induced pluripotent stem cells could be used to generate cardiac tissues for regenerative purposes. Here the authors describe a method to obtain large bioengineered heart tissues showing advanced maturation, functional features and engraftment capacity.Ilya Y. ShadrinBrian W. AllenYing QianChristopher P. JackmanAaron L. CarlsonMark E. JuhasNenad BursacNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ilya Y. Shadrin
Brian W. Allen
Ying Qian
Christopher P. Jackman
Aaron L. Carlson
Mark E. Juhas
Nenad Bursac
Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues
description Cardiomyocytes derived from human induced pluripotent stem cells could be used to generate cardiac tissues for regenerative purposes. Here the authors describe a method to obtain large bioengineered heart tissues showing advanced maturation, functional features and engraftment capacity.
format article
author Ilya Y. Shadrin
Brian W. Allen
Ying Qian
Christopher P. Jackman
Aaron L. Carlson
Mark E. Juhas
Nenad Bursac
author_facet Ilya Y. Shadrin
Brian W. Allen
Ying Qian
Christopher P. Jackman
Aaron L. Carlson
Mark E. Juhas
Nenad Bursac
author_sort Ilya Y. Shadrin
title Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues
title_short Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues
title_full Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues
title_fullStr Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues
title_full_unstemmed Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues
title_sort cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/cf30a3c33e6d47d2acb195744c55d771
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