Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues
Cardiomyocytes derived from human induced pluripotent stem cells could be used to generate cardiac tissues for regenerative purposes. Here the authors describe a method to obtain large bioengineered heart tissues showing advanced maturation, functional features and engraftment capacity.
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Nature Portfolio
2017
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oai:doaj.org-article:cf30a3c33e6d47d2acb195744c55d7712021-12-02T14:40:59ZCardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues10.1038/s41467-017-01946-x2041-1723https://doaj.org/article/cf30a3c33e6d47d2acb195744c55d7712017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01946-xhttps://doaj.org/toc/2041-1723Cardiomyocytes derived from human induced pluripotent stem cells could be used to generate cardiac tissues for regenerative purposes. Here the authors describe a method to obtain large bioengineered heart tissues showing advanced maturation, functional features and engraftment capacity.Ilya Y. ShadrinBrian W. AllenYing QianChristopher P. JackmanAaron L. CarlsonMark E. JuhasNenad BursacNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017) |
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Science Q |
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Science Q Ilya Y. Shadrin Brian W. Allen Ying Qian Christopher P. Jackman Aaron L. Carlson Mark E. Juhas Nenad Bursac Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues |
description |
Cardiomyocytes derived from human induced pluripotent stem cells could be used to generate cardiac tissues for regenerative purposes. Here the authors describe a method to obtain large bioengineered heart tissues showing advanced maturation, functional features and engraftment capacity. |
format |
article |
author |
Ilya Y. Shadrin Brian W. Allen Ying Qian Christopher P. Jackman Aaron L. Carlson Mark E. Juhas Nenad Bursac |
author_facet |
Ilya Y. Shadrin Brian W. Allen Ying Qian Christopher P. Jackman Aaron L. Carlson Mark E. Juhas Nenad Bursac |
author_sort |
Ilya Y. Shadrin |
title |
Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues |
title_short |
Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues |
title_full |
Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues |
title_fullStr |
Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues |
title_full_unstemmed |
Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues |
title_sort |
cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/cf30a3c33e6d47d2acb195744c55d771 |
work_keys_str_mv |
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_version_ |
1718390082066448384 |