Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues

Cardiomyocytes derived from human induced pluripotent stem cells could be used to generate cardiac tissues for regenerative purposes. Here the authors describe a method to obtain large bioengineered heart tissues showing advanced maturation, functional features and engraftment capacity.

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Bibliographic Details
Main Authors:	Ilya Y. Shadrin, Brian W. Allen, Ying Qian, Christopher P. Jackman, Aaron L. Carlson, Mark E. Juhas, Nenad Bursac
Format:	article
Language:	EN
Published:	Nature Portfolio 2017
Subjects:	Science Q
Online Access:	https://doaj.org/article/cf30a3c33e6d47d2acb195744c55d771
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id	oai:doaj.org-article:cf30a3c33e6d47d2acb195744c55d771
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spelling	oai:doaj.org-article:cf30a3c33e6d47d2acb195744c55d7712021-12-02T14:40:59ZCardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues10.1038/s41467-017-01946-x2041-1723https://doaj.org/article/cf30a3c33e6d47d2acb195744c55d7712017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01946-xhttps://doaj.org/toc/2041-1723Cardiomyocytes derived from human induced pluripotent stem cells could be used to generate cardiac tissues for regenerative purposes. Here the authors describe a method to obtain large bioengineered heart tissues showing advanced maturation, functional features and engraftment capacity.Ilya Y. ShadrinBrian W. AllenYing QianChristopher P. JackmanAaron L. CarlsonMark E. JuhasNenad BursacNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ilya Y. Shadrin Brian W. Allen Ying Qian Christopher P. Jackman Aaron L. Carlson Mark E. Juhas Nenad Bursac Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues
description	Cardiomyocytes derived from human induced pluripotent stem cells could be used to generate cardiac tissues for regenerative purposes. Here the authors describe a method to obtain large bioengineered heart tissues showing advanced maturation, functional features and engraftment capacity.
format	article
author	Ilya Y. Shadrin Brian W. Allen Ying Qian Christopher P. Jackman Aaron L. Carlson Mark E. Juhas Nenad Bursac
author_facet	Ilya Y. Shadrin Brian W. Allen Ying Qian Christopher P. Jackman Aaron L. Carlson Mark E. Juhas Nenad Bursac
author_sort	Ilya Y. Shadrin
title	Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues
title_short	Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues
title_full	Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues
title_fullStr	Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues
title_full_unstemmed	Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues
title_sort	cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/cf30a3c33e6d47d2acb195744c55d771
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Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues

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