The Polycomb group protein CBX6 is an essential regulator of embryonic stem cell identity

The Polycomb group protein CBX6 is an essential regulator of embryonic stem cell identity

In mammals, five different CBX proteins can be part of Polycomb repressive complex 1 (PRC1). Here, the authors provide evidence that CBX6 plays an essential role in regulating pluripotency in embryonic stem cells and that CBX6 functions as part of both canonical and non-canonical PRC1 complexes.

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Bibliographic Details
Main Authors: Alexandra Santanach, Enrique Blanco, Hua Jiang, Kelly R. Molloy, Miriam Sansó, John LaCava, Lluis Morey, Luciano Di Croce
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Science
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Online Access:https://doaj.org/article/cf337e53504d4dbca5db1c546d985bc4
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