Local DNA shape is a general principle of transcription factor binding specificity in Arabidopsis thaliana

Methods to predict transcription factor binding sites typically focus on sequence motifs without considering DNA shape. Here the authors use a random forest machine learning approach that incorporates DNA shape and improves binding site prediction for Arabidopsis thaliana transcription factors.

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Autores principales: Janik Sielemann, Donat Wulf, Romy Schmidt, Andrea Bräutigam
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/cf39f456ff7a42b1a4a99eb3f1b5ea9d
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