Local DNA shape is a general principle of transcription factor binding specificity in Arabidopsis thaliana
Methods to predict transcription factor binding sites typically focus on sequence motifs without considering DNA shape. Here the authors use a random forest machine learning approach that incorporates DNA shape and improves binding site prediction for Arabidopsis thaliana transcription factors.
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Autores principales: | Janik Sielemann, Donat Wulf, Romy Schmidt, Andrea Bräutigam |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/cf39f456ff7a42b1a4a99eb3f1b5ea9d |
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