Improvement Of Inactivated Equine Herpes Virus-1 Vaccine Using Carbomer

An inactivated Equine herpes virus-1 vaccine was successfully improved using carbomer as adjuvant inducing high and long immunity in vaccinated mares in comparison with the convention one adjuvanted with Al-hydra gel and saponin. Such purpose was established by using 0.5% carbomer as adjuvant to the...

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Autores principales:	Safaa, A. Warda, Naglaa, I. Ali, Fatma, F. Warda, Ekbal, M. Farouk, Lubna, F. Farahat
Formato:	article
Lenguaje:	EN
Publicado:	Egyptian Society for Animal Management 2021
Materias:	carbomer elisa snt inactivated ehv-1 equine virus Zoology QL1-991 Veterinary medicine SF600-1100 Animal biochemistry QP501-801
Acceso en línea:	https://dx.doi.org/10.21608/javs.2021.140080 https://doaj.org/article/cf3ac03878a74dc89af6fc7988e12cec
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spelling	oai:doaj.org-article:cf3ac03878a74dc89af6fc7988e12cec2021-12-02T17:04:20ZImprovement Of Inactivated Equine Herpes Virus-1 Vaccine Using Carbomerhttps://dx.doi.org/10.21608/javs.2021.1400801687-40722090-3308https://doaj.org/article/cf3ac03878a74dc89af6fc7988e12cec2021-01-01T00:00:00Zhttps://javs.journals.ekb.eg/article_140080.htmlhttps://doaj.org/toc/1687-4072https://doaj.org/toc/2090-3308An inactivated Equine herpes virus-1 vaccine was successfully improved using carbomer as adjuvant inducing high and long immunity in vaccinated mares in comparison with the convention one adjuvanted with Al-hydra gel and saponin. Such purpose was established by using 0.5% carbomer as adjuvant to the inactivated EHV-1. The applied quality control tests carried out on such vaccine revealed that it is free from foreign contaminants, safe in pregnant mares and mice and potent induced high levels of specific EHV-1 antibodies in vaccinated Guinea pigs and mares as measure by ELISA and SNT. This immunity was sufficient to protect vaccinated horses up to 28 weeks (7months) post-vaccination.Safaa, A. WardaNaglaa, I. AliFatma, F. WardaEkbal, M. FaroukLubna, F. FarahatEgyptian Society for Animal Managementarticlecarbomerelisasntinactivated ehv-1equine virusZoologyQL1-991Veterinary medicineSF600-1100Animal biochemistryQP501-801ENJournal of Applied Veterinary Sciences, Vol 6, Iss 1, Pp 21-27 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	carbomer elisa snt inactivated ehv-1 equine virus Zoology QL1-991 Veterinary medicine SF600-1100 Animal biochemistry QP501-801
spellingShingle	carbomer elisa snt inactivated ehv-1 equine virus Zoology QL1-991 Veterinary medicine SF600-1100 Animal biochemistry QP501-801 Safaa, A. Warda Naglaa, I. Ali Fatma, F. Warda Ekbal, M. Farouk Lubna, F. Farahat Improvement Of Inactivated Equine Herpes Virus-1 Vaccine Using Carbomer
description	An inactivated Equine herpes virus-1 vaccine was successfully improved using carbomer as adjuvant inducing high and long immunity in vaccinated mares in comparison with the convention one adjuvanted with Al-hydra gel and saponin. Such purpose was established by using 0.5% carbomer as adjuvant to the inactivated EHV-1. The applied quality control tests carried out on such vaccine revealed that it is free from foreign contaminants, safe in pregnant mares and mice and potent induced high levels of specific EHV-1 antibodies in vaccinated Guinea pigs and mares as measure by ELISA and SNT. This immunity was sufficient to protect vaccinated horses up to 28 weeks (7months) post-vaccination.
format	article
author	Safaa, A. Warda Naglaa, I. Ali Fatma, F. Warda Ekbal, M. Farouk Lubna, F. Farahat
author_facet	Safaa, A. Warda Naglaa, I. Ali Fatma, F. Warda Ekbal, M. Farouk Lubna, F. Farahat
author_sort	Safaa, A. Warda
title	Improvement Of Inactivated Equine Herpes Virus-1 Vaccine Using Carbomer
title_short	Improvement Of Inactivated Equine Herpes Virus-1 Vaccine Using Carbomer
title_full	Improvement Of Inactivated Equine Herpes Virus-1 Vaccine Using Carbomer
title_fullStr	Improvement Of Inactivated Equine Herpes Virus-1 Vaccine Using Carbomer
title_full_unstemmed	Improvement Of Inactivated Equine Herpes Virus-1 Vaccine Using Carbomer
title_sort	improvement of inactivated equine herpes virus-1 vaccine using carbomer
publisher	Egyptian Society for Animal Management
publishDate	2021
url	https://dx.doi.org/10.21608/javs.2021.140080 https://doaj.org/article/cf3ac03878a74dc89af6fc7988e12cec
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Improvement Of Inactivated Equine Herpes Virus-1 Vaccine Using Carbomer

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