Hepatic Adenomatosis in a Young Asymptomatic but High-risk Patient: An Incidental Diagnosis with Potentially Severe Clinical Implications

Hepatic adenomatosis (HA) is a very rare condition and defined as the presence of 10 or more adenomas in an otherwise normal liver. HA has an incidence of 10–24% in patient with hepatic adenoma and it is more common in women. Most patients with HA are asymptomatic with a normal liver function test a...

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Autores principales:	Davide Lanza, Mentor Bilali
Formato:	article
Lenguaje:	EN
Publicado:	SMC MEDIA SRL 2021
Materias:	hepatic adenomatosis hepatic adenoma focal nodular hyperplasia steatosis hepatis Medicine R
Acceso en línea:	https://doaj.org/article/cf4df52025134257a20081da985a7417
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spelling	oai:doaj.org-article:cf4df52025134257a20081da985a74172021-11-09T11:22:41ZHepatic Adenomatosis in a Young Asymptomatic but High-risk Patient: An Incidental Diagnosis with Potentially Severe Clinical Implications2284-259410.12890/2021_002999https://doaj.org/article/cf4df52025134257a20081da985a74172021-11-01T00:00:00Zhttps://www.ejcrim.com/index.php/EJCRIM/article/view/2999https://doaj.org/toc/2284-2594Hepatic adenomatosis (HA) is a very rare condition and defined as the presence of 10 or more adenomas in an otherwise normal liver. HA has an incidence of 10–24% in patient with hepatic adenoma and it is more common in women. Most patients with HA are asymptomatic with a normal liver function test and half of cases are detected incidentally on imaging. Although HA is considered a benign disease, some patients may develop potentially fatal complications, such as hypovolaemic shock due to rupture of the liver lesion or malignant transformation to hepatocellular carcinoma. We report the case of a 29-year-old woman who presented to the emergency room after a car accident. Whole-body computed tomography revealed multiple focal hepatic hypervascular lesions in the right lobe of the liver together with a fatty liver. Subsequent hepatic magnetic resonance imaging suggested the diagnosis of HA with a suspicion of focal nodular hyperplasia (FNH). The patient refused to undergo liver biopsy, so we instituted a 3-month surveillance program, which included clinical assessment, liver function tests, tumour marker assessment and blood tests as well as sonographic evaluation for follow-up of the liver lesions.Davide LanzaMentor BilaliSMC MEDIA SRLarticlehepatic adenomatosishepatic adenoma focal nodular hyperplasiasteatosis hepatisMedicineRENEuropean Journal of Case Reports in Internal Medicine (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	hepatic adenomatosis hepatic adenoma focal nodular hyperplasia steatosis hepatis Medicine R
spellingShingle	hepatic adenomatosis hepatic adenoma focal nodular hyperplasia steatosis hepatis Medicine R Davide Lanza Mentor Bilali Hepatic Adenomatosis in a Young Asymptomatic but High-risk Patient: An Incidental Diagnosis with Potentially Severe Clinical Implications
description	Hepatic adenomatosis (HA) is a very rare condition and defined as the presence of 10 or more adenomas in an otherwise normal liver. HA has an incidence of 10–24% in patient with hepatic adenoma and it is more common in women. Most patients with HA are asymptomatic with a normal liver function test and half of cases are detected incidentally on imaging. Although HA is considered a benign disease, some patients may develop potentially fatal complications, such as hypovolaemic shock due to rupture of the liver lesion or malignant transformation to hepatocellular carcinoma. We report the case of a 29-year-old woman who presented to the emergency room after a car accident. Whole-body computed tomography revealed multiple focal hepatic hypervascular lesions in the right lobe of the liver together with a fatty liver. Subsequent hepatic magnetic resonance imaging suggested the diagnosis of HA with a suspicion of focal nodular hyperplasia (FNH). The patient refused to undergo liver biopsy, so we instituted a 3-month surveillance program, which included clinical assessment, liver function tests, tumour marker assessment and blood tests as well as sonographic evaluation for follow-up of the liver lesions.
format	article
author	Davide Lanza Mentor Bilali
author_facet	Davide Lanza Mentor Bilali
author_sort	Davide Lanza
title	Hepatic Adenomatosis in a Young Asymptomatic but High-risk Patient: An Incidental Diagnosis with Potentially Severe Clinical Implications
title_short	Hepatic Adenomatosis in a Young Asymptomatic but High-risk Patient: An Incidental Diagnosis with Potentially Severe Clinical Implications
title_full	Hepatic Adenomatosis in a Young Asymptomatic but High-risk Patient: An Incidental Diagnosis with Potentially Severe Clinical Implications
title_fullStr	Hepatic Adenomatosis in a Young Asymptomatic but High-risk Patient: An Incidental Diagnosis with Potentially Severe Clinical Implications
title_full_unstemmed	Hepatic Adenomatosis in a Young Asymptomatic but High-risk Patient: An Incidental Diagnosis with Potentially Severe Clinical Implications
title_sort	hepatic adenomatosis in a young asymptomatic but high-risk patient: an incidental diagnosis with potentially severe clinical implications
publisher	SMC MEDIA SRL
publishDate	2021
url	https://doaj.org/article/cf4df52025134257a20081da985a7417
work_keys_str_mv	AT davidelanza hepaticadenomatosisinayoungasymptomaticbuthighriskpatientanincidentaldiagnosiswithpotentiallysevereclinicalimplications AT mentorbilali hepaticadenomatosisinayoungasymptomaticbuthighriskpatientanincidentaldiagnosiswithpotentiallysevereclinicalimplications
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Hepatic Adenomatosis in a Young Asymptomatic but High-risk Patient: An Incidental Diagnosis with Potentially Severe Clinical Implications

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