Fibrinogen and rhegmatogenous retinal detachment: a pilot prospective study

IP TheocharisOphthalmology Department, Iaso General Hospital, Athens, GreecePurpose: To examine the correlation, if any, between fibrinogen plasma levels (FPL) and the clinical features of rhegmatogenous retinal detachment (RRD).Methods: FPL were measured preoperatively in 33 patients with primary R...

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Main Author: IP Theocharis
Format: article
Language:EN
Published: Dove Medical Press 2010
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Online Access:https://doaj.org/article/cf5d5db6059b41a7939cbf6fd6cdeade
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spelling oai:doaj.org-article:cf5d5db6059b41a7939cbf6fd6cdeade2021-12-02T07:44:58ZFibrinogen and rhegmatogenous retinal detachment: a pilot prospective study1177-54671177-5483https://doaj.org/article/cf5d5db6059b41a7939cbf6fd6cdeade2010-02-01T00:00:00Zhttp://www.dovepress.com/fibrinogen-and-rhegmatogenous-retinal-detachment-a-pilot-prospective-s-a3974https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483IP TheocharisOphthalmology Department, Iaso General Hospital, Athens, GreecePurpose: To examine the correlation, if any, between fibrinogen plasma levels (FPL) and the clinical features of rhegmatogenous retinal detachment (RRD).Methods: FPL were measured preoperatively in 33 patients with primary RRD. Patient characteristics and detachment features such as the numbers of breaks and the extent of the detachment were recorded;Results: No statistically significant correlation was found between FPL and the number of breaks. A statistically significant correlation was found between FPL and the extent of the RRD, even if the influence of the number of breaks was excluded. Conclusions: FPL correlate with retinal detachment extent, which implicates an acute inflammatory response to detachment traumatic phenomenon or a role of the fibrinogen molecule in retinal adhesiveness.Keywords: fibrinogen, retinal detachment, pathogenesis IP TheocharisDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2010, Iss default, Pp 73-76 (2010)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
IP Theocharis
Fibrinogen and rhegmatogenous retinal detachment: a pilot prospective study
description IP TheocharisOphthalmology Department, Iaso General Hospital, Athens, GreecePurpose: To examine the correlation, if any, between fibrinogen plasma levels (FPL) and the clinical features of rhegmatogenous retinal detachment (RRD).Methods: FPL were measured preoperatively in 33 patients with primary RRD. Patient characteristics and detachment features such as the numbers of breaks and the extent of the detachment were recorded;Results: No statistically significant correlation was found between FPL and the number of breaks. A statistically significant correlation was found between FPL and the extent of the RRD, even if the influence of the number of breaks was excluded. Conclusions: FPL correlate with retinal detachment extent, which implicates an acute inflammatory response to detachment traumatic phenomenon or a role of the fibrinogen molecule in retinal adhesiveness.Keywords: fibrinogen, retinal detachment, pathogenesis
format article
author IP Theocharis
author_facet IP Theocharis
author_sort IP Theocharis
title Fibrinogen and rhegmatogenous retinal detachment: a pilot prospective study
title_short Fibrinogen and rhegmatogenous retinal detachment: a pilot prospective study
title_full Fibrinogen and rhegmatogenous retinal detachment: a pilot prospective study
title_fullStr Fibrinogen and rhegmatogenous retinal detachment: a pilot prospective study
title_full_unstemmed Fibrinogen and rhegmatogenous retinal detachment: a pilot prospective study
title_sort fibrinogen and rhegmatogenous retinal detachment: a pilot prospective study
publisher Dove Medical Press
publishDate 2010
url https://doaj.org/article/cf5d5db6059b41a7939cbf6fd6cdeade
work_keys_str_mv AT iptheocharis fibrinogenandrhegmatogenousretinaldetachmentapilotprospectivestudy
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