D4F alleviates macrophage-derived foam cell apoptosis by inhibiting the NF-κB-dependent Fas/FasL pathway

D4F alleviates macrophage-derived foam cell apoptosis by inhibiting the NF-κB-dependent Fas/FasL pathway

Abstract This study was designed to explore the protective effect of D4F, an apolipoprotein A-I mimetic peptide, on nuclear factor-κB (NF-κB)-dependent Fas/Fas ligand (FasL) pathway-mediated apoptosis in macrophages induced by oxidized low-density lipoprotein (ox-LDL). Our results showed that ox-LDL...

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Autores principales: Hua Tian, Shu-tong Yao, Na-na Yang, Jie Ren, Peng Jiao, Xiangjian Zhang, Dong-xuan Li, Gong-an Zhang, Zhen-fang Xia, Shu-cun Qin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/cf5f2cd092cc49b7a15da1b1a34d4bf6
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