Pathogen reduction technology for blood component: A promising solution for prevention of emerging infectious disease and bacterial contamination in blood transfusion services

With the rapid evolving of emerging pathogens and residual risk of bacterial contamination in platelets, they continue to pose a constant threat to the safety of blood supply despite effort implemented to mitigate such risk via conventional measures and testing. Three photochemical based advanced pa...

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Autores principales:	Hong Liu, Xun Wang
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Pathogen reduction technology PR system Pathogen reduction Emerging infectious disease Transfusion-transmitted infection, Blood safety Virus Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/cf66cc645a144aa9818b66c221012edb
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spelling	oai:doaj.org-article:cf66cc645a144aa9818b66c221012edb2021-11-04T04:40:25ZPathogen reduction technology for blood component: A promising solution for prevention of emerging infectious disease and bacterial contamination in blood transfusion services2666-469010.1016/j.jpap.2021.100079https://doaj.org/article/cf66cc645a144aa9818b66c221012edb2021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2666469021000646https://doaj.org/toc/2666-4690With the rapid evolving of emerging pathogens and residual risk of bacterial contamination in platelets, they continue to pose a constant threat to the safety of blood supply despite effort implemented to mitigate such risk via conventional measures and testing. Three photochemical based advanced pathogen reduction technology (PRT) that utilize amotosalen, riboflavin and UVC only offer some of the unique advantages over conventional approaches. They have demonstrated superior pathogen reduction capability against various emerging viruses, bacteria, parasites and leukocytes, as well as acceptable safety and clinical efficacy based on reports, studies and clinical trials. Although concern related to cost and adverse transfusion reaction of PRT application remains, with further study and continue improvement, future PRT will continue to play a paramount role in assuring the safety of blood and blood products.Hong LiuXun WangElsevierarticlePathogen reduction technologyPR systemPathogen reductionEmerging infectious diseaseTransfusion-transmitted infection, Blood safetyVirusChemistryQD1-999ENJournal of Photochemistry and Photobiology, Vol 8, Iss , Pp 100079- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Pathogen reduction technology PR system Pathogen reduction Emerging infectious disease Transfusion-transmitted infection, Blood safety Virus Chemistry QD1-999
spellingShingle	Pathogen reduction technology PR system Pathogen reduction Emerging infectious disease Transfusion-transmitted infection, Blood safety Virus Chemistry QD1-999 Hong Liu Xun Wang Pathogen reduction technology for blood component: A promising solution for prevention of emerging infectious disease and bacterial contamination in blood transfusion services
description	With the rapid evolving of emerging pathogens and residual risk of bacterial contamination in platelets, they continue to pose a constant threat to the safety of blood supply despite effort implemented to mitigate such risk via conventional measures and testing. Three photochemical based advanced pathogen reduction technology (PRT) that utilize amotosalen, riboflavin and UVC only offer some of the unique advantages over conventional approaches. They have demonstrated superior pathogen reduction capability against various emerging viruses, bacteria, parasites and leukocytes, as well as acceptable safety and clinical efficacy based on reports, studies and clinical trials. Although concern related to cost and adverse transfusion reaction of PRT application remains, with further study and continue improvement, future PRT will continue to play a paramount role in assuring the safety of blood and blood products.
format	article
author	Hong Liu Xun Wang
author_facet	Hong Liu Xun Wang
author_sort	Hong Liu
title	Pathogen reduction technology for blood component: A promising solution for prevention of emerging infectious disease and bacterial contamination in blood transfusion services
title_short	Pathogen reduction technology for blood component: A promising solution for prevention of emerging infectious disease and bacterial contamination in blood transfusion services
title_full	Pathogen reduction technology for blood component: A promising solution for prevention of emerging infectious disease and bacterial contamination in blood transfusion services
title_fullStr	Pathogen reduction technology for blood component: A promising solution for prevention of emerging infectious disease and bacterial contamination in blood transfusion services
title_full_unstemmed	Pathogen reduction technology for blood component: A promising solution for prevention of emerging infectious disease and bacterial contamination in blood transfusion services
title_sort	pathogen reduction technology for blood component: a promising solution for prevention of emerging infectious disease and bacterial contamination in blood transfusion services
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/cf66cc645a144aa9818b66c221012edb
work_keys_str_mv	AT hongliu pathogenreductiontechnologyforbloodcomponentapromisingsolutionforpreventionofemerginginfectiousdiseaseandbacterialcontaminationinbloodtransfusionservices AT xunwang pathogenreductiontechnologyforbloodcomponentapromisingsolutionforpreventionofemerginginfectiousdiseaseandbacterialcontaminationinbloodtransfusionservices
_version_	1718445240828821504

Pathogen reduction technology for blood component: A promising solution for prevention of emerging infectious disease and bacterial contamination in blood transfusion services

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