Valpromide Inhibits Lytic Cycle Reactivation of Epstein-Barr Virus

ABSTRACT Reactivation of Epstein-Barr virus (EBV) from latency into the lytic phase of its life cycle allows the virus to spread among cells and between hosts. Valproic acid (VPA) inhibits initiation of the lytic cycle in EBV-infected B lymphoma cells. While VPA blocks viral lytic gene expression, i...

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Autores principales: Kelly L. Gorres, Derek Daigle, Sudharshan Mohanram, Grace E. McInerney, Danielle E. Lyons, George Miller
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2016
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Acceso en línea:https://doaj.org/article/cf69ace380fa4a8f868716425cabda6e
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