FREQUENCY OF INSULIN RESISTANCE IN PATIENTS OF POLYCYSTIC OVARY SYNDROME

Objective: The objective of this study was to determine frequency of insulin resistance (IR) in patients of polycystic ovary syndrome. Study Design: Cross sectional analytic study. Place and Duration of Study: This study was conducted in at Department of Chemical Pathology and Endocrinology, C...

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Autores principales: Majida Farooq, Muhammad Farooq, Muhammad Rafi Butt, Sameen Alam, Muhammad Zubair, Sajida Shaheen
Formato: article
Lenguaje:EN
Publicado: Army Medical College Rawalpindi 2019
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Acceso en línea:https://doaj.org/article/cf7b47a938be4ce6825e54273189aecb
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spelling oai:doaj.org-article:cf7b47a938be4ce6825e54273189aecb2021-11-11T04:26:35ZFREQUENCY OF INSULIN RESISTANCE IN PATIENTS OF POLYCYSTIC OVARY SYNDROME0030-96482411-8842https://doaj.org/article/cf7b47a938be4ce6825e54273189aecb2019-08-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/3204/2313https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: The objective of this study was to determine frequency of insulin resistance (IR) in patients of polycystic ovary syndrome. Study Design: Cross sectional analytic study. Place and Duration of Study: This study was conducted in at Department of Chemical Pathology and Endocrinology, CMH Lahore for a period of 6 months, from Oct 2015 to Mar 2016. Material and Methods: Fifteen to thirty five years old female patients already diagnosed to have polycystic ovary syndrome (PCOS), according to Rotterdam Criteria 2003 for at least 6 months were included in this study. Patients who had pregnancy or history of childbirth less than three months back, diabetes mellitus, adrenal or thyroid dysfunction or taken insulin sensitizing agent within last three months were excluded. Two hundred patients fulfilling inclusion criteria were enrolled and blood samples were drawn for analysis of fasting plasma glucose and serum insulin from all of them. Data was entered in a specially designed proforma. The data was analyzed by using SPSS version 17.0 Results: Insulin resistance was found in 137 (69%) enrolled patients in our study. Out of 200 patients 94 (47%) were >25 years and 106 (53%) were <25 years of age. Conclusion: The results of our study showed that a significant proportion of PCOS patients had insulin resistance. A strategy should be made to screen all patients for IR and promote treatment which could prevent IR and its adverse effects.Majida FarooqMuhammad FarooqMuhammad Rafi ButtSameen AlamMuhammad ZubairSajida ShaheenArmy Medical College Rawalpindiarticlehomeostasis model assessment for insulin resistance (homa-ir)insulin resistance (ir)MedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 69, Iss 4, Pp 808-813 (2019)
institution DOAJ
collection DOAJ
language EN
topic homeostasis model assessment for insulin resistance (homa-ir)
insulin resistance (ir)
Medicine
R
Medicine (General)
R5-920
spellingShingle homeostasis model assessment for insulin resistance (homa-ir)
insulin resistance (ir)
Medicine
R
Medicine (General)
R5-920
Majida Farooq
Muhammad Farooq
Muhammad Rafi Butt
Sameen Alam
Muhammad Zubair
Sajida Shaheen
FREQUENCY OF INSULIN RESISTANCE IN PATIENTS OF POLYCYSTIC OVARY SYNDROME
description Objective: The objective of this study was to determine frequency of insulin resistance (IR) in patients of polycystic ovary syndrome. Study Design: Cross sectional analytic study. Place and Duration of Study: This study was conducted in at Department of Chemical Pathology and Endocrinology, CMH Lahore for a period of 6 months, from Oct 2015 to Mar 2016. Material and Methods: Fifteen to thirty five years old female patients already diagnosed to have polycystic ovary syndrome (PCOS), according to Rotterdam Criteria 2003 for at least 6 months were included in this study. Patients who had pregnancy or history of childbirth less than three months back, diabetes mellitus, adrenal or thyroid dysfunction or taken insulin sensitizing agent within last three months were excluded. Two hundred patients fulfilling inclusion criteria were enrolled and blood samples were drawn for analysis of fasting plasma glucose and serum insulin from all of them. Data was entered in a specially designed proforma. The data was analyzed by using SPSS version 17.0 Results: Insulin resistance was found in 137 (69%) enrolled patients in our study. Out of 200 patients 94 (47%) were >25 years and 106 (53%) were <25 years of age. Conclusion: The results of our study showed that a significant proportion of PCOS patients had insulin resistance. A strategy should be made to screen all patients for IR and promote treatment which could prevent IR and its adverse effects.
format article
author Majida Farooq
Muhammad Farooq
Muhammad Rafi Butt
Sameen Alam
Muhammad Zubair
Sajida Shaheen
author_facet Majida Farooq
Muhammad Farooq
Muhammad Rafi Butt
Sameen Alam
Muhammad Zubair
Sajida Shaheen
author_sort Majida Farooq
title FREQUENCY OF INSULIN RESISTANCE IN PATIENTS OF POLYCYSTIC OVARY SYNDROME
title_short FREQUENCY OF INSULIN RESISTANCE IN PATIENTS OF POLYCYSTIC OVARY SYNDROME
title_full FREQUENCY OF INSULIN RESISTANCE IN PATIENTS OF POLYCYSTIC OVARY SYNDROME
title_fullStr FREQUENCY OF INSULIN RESISTANCE IN PATIENTS OF POLYCYSTIC OVARY SYNDROME
title_full_unstemmed FREQUENCY OF INSULIN RESISTANCE IN PATIENTS OF POLYCYSTIC OVARY SYNDROME
title_sort frequency of insulin resistance in patients of polycystic ovary syndrome
publisher Army Medical College Rawalpindi
publishDate 2019
url https://doaj.org/article/cf7b47a938be4ce6825e54273189aecb
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