The Hypothesis of the COVID-19 Role in Acute kidney Injury: A Literatures Review

Coronavirus disease 2019 (COVID-2019) is a viral infection that mainly causes pulmonary infection but mortality usually occurred in patients have comorbidities, such as chronic kidney disease (CKD) that accounts for over 20% of mortalities, morbid obesity, immunosuppression, diabetes mellitus, hyper...

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Autores principales:	Abdolreza Mohammadi, Seyed Mohammad Kazem Aghamir
Formato:	article
Lenguaje:	EN
Publicado:	Urology Research Center 2020
Materias:	acute kidney injury acute tubular necrosis chronic kidney disease covid-2019 infection Diseases of the genitourinary system. Urology RC870-923
Acceso en línea:	https://doaj.org/article/cf81115348454dfba66ef1cea24b8a40
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spelling	oai:doaj.org-article:cf81115348454dfba66ef1cea24b8a402021-11-29T07:26:41ZThe Hypothesis of the COVID-19 Role in Acute kidney Injury: A Literatures Review10.22034/TRU.2020.255389.10402717-042Xhttps://doaj.org/article/cf81115348454dfba66ef1cea24b8a402020-08-01T00:00:00Zhttps://www.transresurology.com/article_119469.htmlhttps://doaj.org/toc/2717-042XCoronavirus disease 2019 (COVID-2019) is a viral infection that mainly causes pulmonary infection but mortality usually occurred in patients have comorbidities, such as chronic kidney disease (CKD) that accounts for over 20% of mortalities, morbid obesity, immunosuppression, diabetes mellitus, hypertension, and cancer. Also, the incidence of acute kidney failure reported 5-10% in outpatient series and up to 50% in patients that need to be admitted to the intensive care unit. It is important to know that acute kidney injury (AKI) is associated with increased mortality, so this essay is going to review possible mechanisms that result in AKI. Based on the multifactorial mechanism of AKI, we should have considered probable causes of AKI and act in a stepwise manner to tackle these mechanisms and improve the ultimate prognosis of patients. Although most of the measures are supportive, in some patients such as severely ill cases cytokine storm may be attributed to the severity of symptoms, so immunomodulatory treatments could be considered to decrease AKI and consequently mortality. Among hypotheses that propose AKI; pre-renal and direct renal involvement by a virus are discussed in detail.Abdolreza Mohammadi Seyed Mohammad Kazem AghamirUrology Research Centerarticleacute kidney injuryacute tubular necrosischronic kidney diseasecovid-2019infectionDiseases of the genitourinary system. UrologyRC870-923ENTranslational Research in Urology, Vol 2, Iss 3, Pp 74-78 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	acute kidney injury acute tubular necrosis chronic kidney disease covid-2019 infection Diseases of the genitourinary system. Urology RC870-923
spellingShingle	acute kidney injury acute tubular necrosis chronic kidney disease covid-2019 infection Diseases of the genitourinary system. Urology RC870-923 Abdolreza Mohammadi Seyed Mohammad Kazem Aghamir The Hypothesis of the COVID-19 Role in Acute kidney Injury: A Literatures Review
description	Coronavirus disease 2019 (COVID-2019) is a viral infection that mainly causes pulmonary infection but mortality usually occurred in patients have comorbidities, such as chronic kidney disease (CKD) that accounts for over 20% of mortalities, morbid obesity, immunosuppression, diabetes mellitus, hypertension, and cancer. Also, the incidence of acute kidney failure reported 5-10% in outpatient series and up to 50% in patients that need to be admitted to the intensive care unit. It is important to know that acute kidney injury (AKI) is associated with increased mortality, so this essay is going to review possible mechanisms that result in AKI. Based on the multifactorial mechanism of AKI, we should have considered probable causes of AKI and act in a stepwise manner to tackle these mechanisms and improve the ultimate prognosis of patients. Although most of the measures are supportive, in some patients such as severely ill cases cytokine storm may be attributed to the severity of symptoms, so immunomodulatory treatments could be considered to decrease AKI and consequently mortality. Among hypotheses that propose AKI; pre-renal and direct renal involvement by a virus are discussed in detail.
format	article
author	Abdolreza Mohammadi Seyed Mohammad Kazem Aghamir
author_facet	Abdolreza Mohammadi Seyed Mohammad Kazem Aghamir
author_sort	Abdolreza Mohammadi
title	The Hypothesis of the COVID-19 Role in Acute kidney Injury: A Literatures Review
title_short	The Hypothesis of the COVID-19 Role in Acute kidney Injury: A Literatures Review
title_full	The Hypothesis of the COVID-19 Role in Acute kidney Injury: A Literatures Review
title_fullStr	The Hypothesis of the COVID-19 Role in Acute kidney Injury: A Literatures Review
title_full_unstemmed	The Hypothesis of the COVID-19 Role in Acute kidney Injury: A Literatures Review
title_sort	hypothesis of the covid-19 role in acute kidney injury: a literatures review
publisher	Urology Research Center
publishDate	2020
url	https://doaj.org/article/cf81115348454dfba66ef1cea24b8a40
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The Hypothesis of the COVID-19 Role in Acute kidney Injury: A Literatures Review

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