Vimentin filaments interact with the actin cortex in mitosis allowing normal cell division

The intermediate filament vimentin reorganizes during mitosis, but its molecular regulation and impact on the cell during cell division is unclear. Here, the authors show that vimentin filaments redistribute to the cell cortex during mitosis intertwining with and affecting actin organization.

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Autores principales: Sofia Duarte, Álvaro Viedma-Poyatos, Elena Navarro-Carrasco, Alma E. Martínez, María A. Pajares, Dolores Pérez-Sala
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/cf82cdd422be4ec5b5be0ecec294164e
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Sumario:The intermediate filament vimentin reorganizes during mitosis, but its molecular regulation and impact on the cell during cell division is unclear. Here, the authors show that vimentin filaments redistribute to the cell cortex during mitosis intertwining with and affecting actin organization.