Changing local recombination patterns in Arabidopsis by CRISPR/Cas mediated chromosome engineering
The heterochromatic knob (hk4S) on Arabidopsis chromosome 4 prevents the recombination between accessions with and without hk4S. Here, via egg-cell specific expression of the Cas9 nuclease, the authors demonstrate targeted reversal of the 1.1 Mb long hk4S-inversion in Col-0 and restore the crossover...
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Autores principales: | Carla Schmidt, Paul Fransz, Michelle Rönspies, Steven Dreissig, Jörg Fuchs, Stefan Heckmann, Andreas Houben, Holger Puchta |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/cf83736280954c2b9ce44781961ab796 |
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