Multiple entry pathways within the efflux transporter AcrB contribute to multidrug recognition

Multidrug transporters possess several drug binding sites. Here the authors describe a transport path specific for planar aromatic cations in the E. coli multi-drug transporter AcrB.

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Autores principales:	Martijn Zwama, Seiji Yamasaki, Ryosuke Nakashima, Keisuke Sakurai, Kunihiko Nishino, Akihito Yamaguchi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/cf87738eec424a5bb6b49a27e8fde79a
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spelling	oai:doaj.org-article:cf87738eec424a5bb6b49a27e8fde79a2021-12-02T16:49:55ZMultiple entry pathways within the efflux transporter AcrB contribute to multidrug recognition10.1038/s41467-017-02493-12041-1723https://doaj.org/article/cf87738eec424a5bb6b49a27e8fde79a2018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02493-1https://doaj.org/toc/2041-1723Multidrug transporters possess several drug binding sites. Here the authors describe a transport path specific for planar aromatic cations in the E. coli multi-drug transporter AcrB.Martijn ZwamaSeiji YamasakiRyosuke NakashimaKeisuke SakuraiKunihiko NishinoAkihito YamaguchiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Martijn Zwama Seiji Yamasaki Ryosuke Nakashima Keisuke Sakurai Kunihiko Nishino Akihito Yamaguchi Multiple entry pathways within the efflux transporter AcrB contribute to multidrug recognition
description	Multidrug transporters possess several drug binding sites. Here the authors describe a transport path specific for planar aromatic cations in the E. coli multi-drug transporter AcrB.
format	article
author	Martijn Zwama Seiji Yamasaki Ryosuke Nakashima Keisuke Sakurai Kunihiko Nishino Akihito Yamaguchi
author_facet	Martijn Zwama Seiji Yamasaki Ryosuke Nakashima Keisuke Sakurai Kunihiko Nishino Akihito Yamaguchi
author_sort	Martijn Zwama
title	Multiple entry pathways within the efflux transporter AcrB contribute to multidrug recognition
title_short	Multiple entry pathways within the efflux transporter AcrB contribute to multidrug recognition
title_full	Multiple entry pathways within the efflux transporter AcrB contribute to multidrug recognition
title_fullStr	Multiple entry pathways within the efflux transporter AcrB contribute to multidrug recognition
title_full_unstemmed	Multiple entry pathways within the efflux transporter AcrB contribute to multidrug recognition
title_sort	multiple entry pathways within the efflux transporter acrb contribute to multidrug recognition
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/cf87738eec424a5bb6b49a27e8fde79a
work_keys_str_mv	AT martijnzwama multipleentrypathwayswithintheeffluxtransporteracrbcontributetomultidrugrecognition AT seijiyamasaki multipleentrypathwayswithintheeffluxtransporteracrbcontributetomultidrugrecognition AT ryosukenakashima multipleentrypathwayswithintheeffluxtransporteracrbcontributetomultidrugrecognition AT keisukesakurai multipleentrypathwayswithintheeffluxtransporteracrbcontributetomultidrugrecognition AT kunihikonishino multipleentrypathwayswithintheeffluxtransporteracrbcontributetomultidrugrecognition AT akihitoyamaguchi multipleentrypathwayswithintheeffluxtransporteracrbcontributetomultidrugrecognition
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Multiple entry pathways within the efflux transporter AcrB contribute to multidrug recognition

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