Phosphorylation-Dependent Assembly of a 14-3-3 Mediated Signaling Complex during Red Blood Cell Invasion by <named-content content-type="genus-species">Plasmodium falciparum</named-content> Merozoites

Phosphorylation-Dependent Assembly of a 14-3-3 Mediated Signaling Complex during Red Blood Cell Invasion by <named-content content-type="genus-species">Plasmodium falciparum</named-content> Merozoites

ABSTRACT Red blood cell (RBC) invasion by Plasmodium merozoites requires multiple steps that are regulated by signaling pathways. Exposure of P. falciparum merozoites to the physiological signal of low K+, as found in blood plasma, leads to a rise in cytosolic Ca2+, which mediates microneme secretio...

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Auteurs principaux: Kunal R. More, Inderjeet Kaur, Quentin Giai Gianetto, Brandon M. Invergo, Thibault Chaze, Ravi Jain, Christéle Huon, Petra Gutenbrunner, Hendrik Weisser, Mariette Matondo, Jyoti S. Choudhary, Gordon Langsley, Shailja Singh, Chetan E. Chitnis
Format: article
Langue:EN
Publié: American Society for Microbiology 2020
Sujets:
host cell invasion
host-parasite interaction
malaria
signaling
Microbiology
QR1-502
Accès en ligne:https://doaj.org/article/cf8e5574eaf442db8acf7c08a6cec1bf
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