A new approach to control the enigmatic activity of aldose reductase.
Aldose reductase (AR) is an NADPH-dependent reductase, which acts on a variety of hydrophilic as well as hydrophobic aldehydes. It is currently defined as the first enzyme in the so-called polyol pathway, in which glucose is transformed into sorbitol by AR and then to fructose by an NAD(+)-dependent...
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Autores principales: | Antonella Del-Corso, Francesco Balestri, Elisa Di Bugno, Roberta Moschini, Mario Cappiello, Stefania Sartini, Concettina La-Motta, Federico Da-Settimo, Umberto Mura |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/cf978c944f8142b7a5fa55f15794e781 |
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