Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci

Coronary heart disease is the leading cause of death worldwide with multiple environmental and genetic risk factors. Here the authors integrate genomic, epigenomic and transcriptomic mapping to elucidate causal variation and mechanisms of known genetic associations.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Clint L. Miller, Milos Pjanic, Ting Wang, Trieu Nguyen, Ariella Cohain, Jonathan D. Lee, Ljubica Perisic, Ulf Hedin, Ramendra K. Kundu, Deshna Majmudar, Juyong B. Kim, Oliver Wang, Christer Betsholtz, Arno Ruusalepp, Oscar Franzén, Themistocles L. Assimes, Stephen B. Montgomery, Eric E. Schadt, Johan L.M. Björkegren, Thomas Quertermous
Format: article
Langue:EN
Publié: Nature Portfolio 2016
Sujets:
Q
Accès en ligne:https://doaj.org/article/cf9af3cf26bf44b0ab0e9246393278dd
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!