CTLA-4 blockade in the treatment of colorectal cancer with microsatellite instability

Context: Colorectal cancer is one of the most common tumours worldwide, with around 10-15% of these related to microsatellite instability which is, in turn, responsible for a high neoantigen load and subsequent high tumour mutational burden. These characteristics are responsible for the poor respons...

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Bibliographic Details
Main Authors: Diana Russo, Francisco Mendes
Format: article
Language:EN
Published: Shiraz University of Medical Sciences 2021
Subjects:
R
Online Access:https://doaj.org/article/cf9dbae49f62401a8b71557d294ccb74
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