Comparative genomics search for losses of long-established genes on the human lineage.

Taking advantage of the complete genome sequences of several mammals, we developed a novel method to detect losses of well-established genes in the human genome through syntenic mapping of gene structures between the human, mouse, and dog genomes. Unlike most previous genomic methods for pseudogene...

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Autores principales: Jingchun Zhu, J Zachary Sanborn, Mark Diekhans, Craig B Lowe, Tom H Pringle, David Haussler
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2007
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Acceso en línea:https://doaj.org/article/cfa9ec0326204710889b5fcf5e225899
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