Integration of Metabolomics and Transcriptomics Reveals a Complex Diet of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> during Early Macrophage Infection

Integration of Metabolomics and Transcriptomics Reveals a Complex Diet of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> during Early Macrophage Infection

ABSTRACT Nutrient acquisition from the host environment is crucial for the survival of intracellular pathogens, but conceptual and technical challenges limit our knowledge of pathogen diets. To overcome some of these technical roadblocks, we exploited an experimentally accessible model for early inf...

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Autores principales: Michael Zimmermann, Maria Kogadeeva, Martin Gengenbacher, Gayle McEwen, Hans-Joachim Mollenkopf, Nicola Zamboni, Stefan Hugo Ernst Kaufmann, Uwe Sauer
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
Materias:
Mycobacterium tuberculosis
host-pathogen interactions
metabolism
systems biology
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/cfb445e88e4d4cf48d220a6311bbdad6
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