Identification of a lifespan extending mutation in the Schizosaccharomyces pombe cyclin gene clg1+ by direct selection of long-lived mutants.

Model organisms such as budding yeast, worms and flies have proven instrumental in the discovery of genetic determinants of aging, and the fission yeast Schizosaccharomyces pombe is a promising new system for these studies. We devised an approach to directly select for long-lived S. pombe mutants fr...

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Auteurs principaux: Bo-Ruei Chen, Yanhui Li, Jessica R Eisenstatt, Kurt W Runge
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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R
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Accès en ligne:https://doaj.org/article/cfb69bd784784020aab05c7f4bc8f10c
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