Nanocarriers in the Enhancement of Therapeutic Efficacy of Natural Drugs

Since time immemorial, plant derived natural products have been used for the treatment of various human diseases before the intervention of modern medicine. The basis of modern medicine is still being inspired from traditional medicine and therapies. However, despite their tremendous therapeutic pot...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Xiuling Li, Shunung Liang, Chee Hwee Tan, Shuwen Cao, Xiaoding Xu, Phei Er Saw, Wei Tao
Formato:	article
Lenguaje:	EN
Publicado:	Compuscript Ltd 2021
Materias:	nanocarriers intervention natural drugs therapeutic efficacy Medicine R
Acceso en línea:	https://doaj.org/article/cfbd7ed67aac4db5b835d01e0ab182ce
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:cfbd7ed67aac4db5b835d01e0ab182ce
record_format	dspace
spelling	oai:doaj.org-article:cfbd7ed67aac4db5b835d01e0ab182ce2021-11-09T08:30:25ZNanocarriers in the Enhancement of Therapeutic Efficacy of Natural Drugs2712-008210.15212/bioi-2020-0040https://doaj.org/article/cfbd7ed67aac4db5b835d01e0ab182ce2021-07-01T00:00:00Zhttps://www.ingentaconnect.com/contentone/cscript/bioi/2021/00000002/00000002/art00002https://doaj.org/toc/2712-0082Since time immemorial, plant derived natural products have been used for the treatment of various human diseases before the intervention of modern medicine. The basis of modern medicine is still being inspired from traditional medicine and therapies. However, despite their tremendous therapeutic potential, these natural drugs often have poor bioavailability, metabolic instability, and aqueous insolubility. These factors greatly impede a natural drug’s commercialization potential as a mainstream medicine. Therefore, the development of nanocarrier drug delivery systems is indispensable in overcoming the various constraints of the bottlenecks which occur with natural drugs. Of particular interest in this review are four plant materials endogenous to China with the common names of barrenwort or horny goat weed (Epimedium), Shu Di Huang (Rehmannia glutinosa, RG), ginseng (Panax ginseng), and Dong Quai or female ginseng (Angelica sinensis, AS), each having been scientifically investigated for a wide range of therapeutic uses as has been originally discovered from the long history of traditional usage and anecdotal information by local population groups in Asia. The integration of natural drugs from the East and nanocarrier drug delivery systems developed from the West is paving the way towards further accurate and efficient medicine therapy. We further discuss the potential benefits of these plants and the enhancement of their therapeutic efficacy by nanotechnology intervention.Xiuling LiShunung LiangChee Hwee TanShuwen CaoXiaoding XuPhei Er SawWei TaoCompuscript Ltdarticlenanocarriers interventionnatural drugstherapeutic efficacyMedicineRENBIO Integration, Vol 2, Iss 2, Pp 40-49 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	nanocarriers intervention natural drugs therapeutic efficacy Medicine R
spellingShingle	nanocarriers intervention natural drugs therapeutic efficacy Medicine R Xiuling Li Shunung Liang Chee Hwee Tan Shuwen Cao Xiaoding Xu Phei Er Saw Wei Tao Nanocarriers in the Enhancement of Therapeutic Efficacy of Natural Drugs
description	Since time immemorial, plant derived natural products have been used for the treatment of various human diseases before the intervention of modern medicine. The basis of modern medicine is still being inspired from traditional medicine and therapies. However, despite their tremendous therapeutic potential, these natural drugs often have poor bioavailability, metabolic instability, and aqueous insolubility. These factors greatly impede a natural drug’s commercialization potential as a mainstream medicine. Therefore, the development of nanocarrier drug delivery systems is indispensable in overcoming the various constraints of the bottlenecks which occur with natural drugs. Of particular interest in this review are four plant materials endogenous to China with the common names of barrenwort or horny goat weed (Epimedium), Shu Di Huang (Rehmannia glutinosa, RG), ginseng (Panax ginseng), and Dong Quai or female ginseng (Angelica sinensis, AS), each having been scientifically investigated for a wide range of therapeutic uses as has been originally discovered from the long history of traditional usage and anecdotal information by local population groups in Asia. The integration of natural drugs from the East and nanocarrier drug delivery systems developed from the West is paving the way towards further accurate and efficient medicine therapy. We further discuss the potential benefits of these plants and the enhancement of their therapeutic efficacy by nanotechnology intervention.
format	article
author	Xiuling Li Shunung Liang Chee Hwee Tan Shuwen Cao Xiaoding Xu Phei Er Saw Wei Tao
author_facet	Xiuling Li Shunung Liang Chee Hwee Tan Shuwen Cao Xiaoding Xu Phei Er Saw Wei Tao
author_sort	Xiuling Li
title	Nanocarriers in the Enhancement of Therapeutic Efficacy of Natural Drugs
title_short	Nanocarriers in the Enhancement of Therapeutic Efficacy of Natural Drugs
title_full	Nanocarriers in the Enhancement of Therapeutic Efficacy of Natural Drugs
title_fullStr	Nanocarriers in the Enhancement of Therapeutic Efficacy of Natural Drugs
title_full_unstemmed	Nanocarriers in the Enhancement of Therapeutic Efficacy of Natural Drugs
title_sort	nanocarriers in the enhancement of therapeutic efficacy of natural drugs
publisher	Compuscript Ltd
publishDate	2021
url	https://doaj.org/article/cfbd7ed67aac4db5b835d01e0ab182ce
work_keys_str_mv	AT xiulingli nanocarriersintheenhancementoftherapeuticefficacyofnaturaldrugs AT shunungliang nanocarriersintheenhancementoftherapeuticefficacyofnaturaldrugs AT cheehweetan nanocarriersintheenhancementoftherapeuticefficacyofnaturaldrugs AT shuwencao nanocarriersintheenhancementoftherapeuticefficacyofnaturaldrugs AT xiaodingxu nanocarriersintheenhancementoftherapeuticefficacyofnaturaldrugs AT pheiersaw nanocarriersintheenhancementoftherapeuticefficacyofnaturaldrugs AT weitao nanocarriersintheenhancementoftherapeuticefficacyofnaturaldrugs
_version_	1718441247375360000

Nanocarriers in the Enhancement of Therapeutic Efficacy of Natural Drugs

Ejemplares similares