Cell specific photoswitchable agonist for reversible control of endogenous dopamine receptors

In this study, the authors develop a photo-pharmacological strategy using a Membrane anchored Photoswitchable orthogonal remotely tethered agonist for the Dopamine receptor (MP-D) to selectively and reversibly modulate the D1R receptor subtype.

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Detalles Bibliográficos
Autores principales:	Prashant Donthamsetti, Nils Winter, Adam Hoagland, Cherise Stanley, Meike Visel, Stephan Lammel, Dirk Trauner, Ehud Isacoff
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/cfcb66adbc114a23958d7e4a4ad421e8
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spelling	oai:doaj.org-article:cfcb66adbc114a23958d7e4a4ad421e82021-12-02T18:49:35ZCell specific photoswitchable agonist for reversible control of endogenous dopamine receptors10.1038/s41467-021-25003-w2041-1723https://doaj.org/article/cfcb66adbc114a23958d7e4a4ad421e82021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25003-whttps://doaj.org/toc/2041-1723In this study, the authors develop a photo-pharmacological strategy using a Membrane anchored Photoswitchable orthogonal remotely tethered agonist for the Dopamine receptor (MP-D) to selectively and reversibly modulate the D1R receptor subtype.Prashant DonthamsettiNils WinterAdam HoaglandCherise StanleyMeike ViselStephan LammelDirk TraunerEhud IsacoffNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Prashant Donthamsetti Nils Winter Adam Hoagland Cherise Stanley Meike Visel Stephan Lammel Dirk Trauner Ehud Isacoff Cell specific photoswitchable agonist for reversible control of endogenous dopamine receptors
description	In this study, the authors develop a photo-pharmacological strategy using a Membrane anchored Photoswitchable orthogonal remotely tethered agonist for the Dopamine receptor (MP-D) to selectively and reversibly modulate the D1R receptor subtype.
format	article
author	Prashant Donthamsetti Nils Winter Adam Hoagland Cherise Stanley Meike Visel Stephan Lammel Dirk Trauner Ehud Isacoff
author_facet	Prashant Donthamsetti Nils Winter Adam Hoagland Cherise Stanley Meike Visel Stephan Lammel Dirk Trauner Ehud Isacoff
author_sort	Prashant Donthamsetti
title	Cell specific photoswitchable agonist for reversible control of endogenous dopamine receptors
title_short	Cell specific photoswitchable agonist for reversible control of endogenous dopamine receptors
title_full	Cell specific photoswitchable agonist for reversible control of endogenous dopamine receptors
title_fullStr	Cell specific photoswitchable agonist for reversible control of endogenous dopamine receptors
title_full_unstemmed	Cell specific photoswitchable agonist for reversible control of endogenous dopamine receptors
title_sort	cell specific photoswitchable agonist for reversible control of endogenous dopamine receptors
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/cfcb66adbc114a23958d7e4a4ad421e8
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Cell specific photoswitchable agonist for reversible control of endogenous dopamine receptors

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