Waveguide-PAINT offers an open platform for large field-of-view super-resolution imaging

TIRF imaging is limited by the size and uniformity of the illumination. Here the authors present a waveguide solution to create a large area of uniform evanescent illumination suitable for single molecule imaging coupled with a customised sample holder containing a reservoir for DNA-PAINT solutions.

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Detalles Bibliográficos
Autores principales: Anna Archetti, Evgenii Glushkov, Christian Sieben, Anton Stroganov, Aleksandra Radenovic, Suliana Manley
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/cfceec778eb841798554c99bdf6ae604
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Descripción
Sumario:TIRF imaging is limited by the size and uniformity of the illumination. Here the authors present a waveguide solution to create a large area of uniform evanescent illumination suitable for single molecule imaging coupled with a customised sample holder containing a reservoir for DNA-PAINT solutions.