Waveguide-PAINT offers an open platform for large field-of-view super-resolution imaging

TIRF imaging is limited by the size and uniformity of the illumination. Here the authors present a waveguide solution to create a large area of uniform evanescent illumination suitable for single molecule imaging coupled with a customised sample holder containing a reservoir for DNA-PAINT solutions.

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Autores principales: Anna Archetti, Evgenii Glushkov, Christian Sieben, Anton Stroganov, Aleksandra Radenovic, Suliana Manley
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/cfceec778eb841798554c99bdf6ae604
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spelling oai:doaj.org-article:cfceec778eb841798554c99bdf6ae6042021-12-02T15:35:11ZWaveguide-PAINT offers an open platform for large field-of-view super-resolution imaging10.1038/s41467-019-09247-12041-1723https://doaj.org/article/cfceec778eb841798554c99bdf6ae6042019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09247-1https://doaj.org/toc/2041-1723TIRF imaging is limited by the size and uniformity of the illumination. Here the authors present a waveguide solution to create a large area of uniform evanescent illumination suitable for single molecule imaging coupled with a customised sample holder containing a reservoir for DNA-PAINT solutions.Anna ArchettiEvgenii GlushkovChristian SiebenAnton StroganovAleksandra RadenovicSuliana ManleyNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Anna Archetti
Evgenii Glushkov
Christian Sieben
Anton Stroganov
Aleksandra Radenovic
Suliana Manley
Waveguide-PAINT offers an open platform for large field-of-view super-resolution imaging
description TIRF imaging is limited by the size and uniformity of the illumination. Here the authors present a waveguide solution to create a large area of uniform evanescent illumination suitable for single molecule imaging coupled with a customised sample holder containing a reservoir for DNA-PAINT solutions.
format article
author Anna Archetti
Evgenii Glushkov
Christian Sieben
Anton Stroganov
Aleksandra Radenovic
Suliana Manley
author_facet Anna Archetti
Evgenii Glushkov
Christian Sieben
Anton Stroganov
Aleksandra Radenovic
Suliana Manley
author_sort Anna Archetti
title Waveguide-PAINT offers an open platform for large field-of-view super-resolution imaging
title_short Waveguide-PAINT offers an open platform for large field-of-view super-resolution imaging
title_full Waveguide-PAINT offers an open platform for large field-of-view super-resolution imaging
title_fullStr Waveguide-PAINT offers an open platform for large field-of-view super-resolution imaging
title_full_unstemmed Waveguide-PAINT offers an open platform for large field-of-view super-resolution imaging
title_sort waveguide-paint offers an open platform for large field-of-view super-resolution imaging
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/cfceec778eb841798554c99bdf6ae604
work_keys_str_mv AT annaarchetti waveguidepaintoffersanopenplatformforlargefieldofviewsuperresolutionimaging
AT evgeniiglushkov waveguidepaintoffersanopenplatformforlargefieldofviewsuperresolutionimaging
AT christiansieben waveguidepaintoffersanopenplatformforlargefieldofviewsuperresolutionimaging
AT antonstroganov waveguidepaintoffersanopenplatformforlargefieldofviewsuperresolutionimaging
AT aleksandraradenovic waveguidepaintoffersanopenplatformforlargefieldofviewsuperresolutionimaging
AT sulianamanley waveguidepaintoffersanopenplatformforlargefieldofviewsuperresolutionimaging
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