Characteristics of meningococcal infection morbidity in the Republic of Moldova over the period 2000-2019

Introduction. Meningococcal infection (MI) and N. meningitidis carriage are widespread. The global incidence represents a total of 500,000-1,200,000 cases per year, of which 50,000-135,000 are fatal. In European countries the incidence is 0.6-2.0 per 100,000. Infants and young people are more likely...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Victoria BUCOV, Alexei CEBAN, Ludmila BIRCA
Formato:	article
Lenguaje:	EN FR RO RU
Publicado:	Asociatia de Biosiguranta si Biosecuritate 2020
Materias:	meningococcal infection epidemiology morbidity Medicine R Science Q
Acceso en línea:	https://doaj.org/article/cfcf6ebe020946ada9fc0e689b54bcc1
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:cfcf6ebe020946ada9fc0e689b54bcc1
record_format	dspace
spelling	oai:doaj.org-article:cfcf6ebe020946ada9fc0e689b54bcc12021-12-02T14:17:33ZCharacteristics of meningococcal infection morbidity in the Republic of Moldova over the period 2000-201910.38045/ohrm.2020.1.122887-34582587-3466https://doaj.org/article/cfcf6ebe020946ada9fc0e689b54bcc12020-10-01T00:00:00Zhttps://journal.ohrm.bba.md/index.php/journal-ohrm-bba-md/article/view/75/46https://doaj.org/toc/2887-3458https://doaj.org/toc/2587-3466Introduction. Meningococcal infection (MI) and N. meningitidis carriage are widespread. The global incidence represents a total of 500,000-1,200,000 cases per year, of which 50,000-135,000 are fatal. In European countries the incidence is 0.6-2.0 per 100,000. Infants and young people are more likely to get affected due to different genotypes of meningococci. Thus, MI surveillance is required. Material and methods. The research purpose was to perform an epidemiological analysis of MI in the Republic of Moldova between 2000 and 2019. In the descriptive retrospective epidemiological study were analysed the total MI incidence of a population of 100,000 people, the number of cases in urban and rural areas, the morbidity rate among 1000 children aged between 0 and 17 years, and patients’ age structure. Results. A decreased incidence, without cyclicity, was registered over the past 5 years from 2.57 to 0.55-1.01 per 100,000. The number of carriers accounted for 0.48-0.26 per 100,000 between 2000 and 2005, and zero during 2016-2019. MI vaccination is not carried out. The MI incidence in urban and rural areas was the same. In children aged between 0 and 17 years, during 2000 and 2005, MI incidence was 0.05–0.07, compared to 2016–2019 when it constituted 0.02–0.04 per 1000. In children aged between 0 and 2 years these indices were 0.08 per 1000 in 2004, and 0.44 per 1000 in 2018. Thus, the indices were lower among children aged between 3 and 6 years. Conclusions. Incomplete detection of MI has been noted. Children aged between 0 and 2 years are prone to develop MI, the most vulnerable ones being children aged up to one year. The age structure of patients depends on the intensity of the epidemic process. Hence, it is necessary to improve MI surveillance with genotyping of circulating strains.Victoria BUCOVAlexei CEBANLudmila BIRCAAsociatia de Biosiguranta si Biosecuritatearticlemeningococcal infectionepidemiologymorbidityMedicineRScienceQENFRRORUOne Health & Risk Management, Vol 1, Iss 2, Pp 17-22 (2020)
institution	DOAJ
collection	DOAJ
language	EN FR RO RU
topic	meningococcal infection epidemiology morbidity Medicine R Science Q
spellingShingle	meningococcal infection epidemiology morbidity Medicine R Science Q Victoria BUCOV Alexei CEBAN Ludmila BIRCA Characteristics of meningococcal infection morbidity in the Republic of Moldova over the period 2000-2019
description	Introduction. Meningococcal infection (MI) and N. meningitidis carriage are widespread. The global incidence represents a total of 500,000-1,200,000 cases per year, of which 50,000-135,000 are fatal. In European countries the incidence is 0.6-2.0 per 100,000. Infants and young people are more likely to get affected due to different genotypes of meningococci. Thus, MI surveillance is required. Material and methods. The research purpose was to perform an epidemiological analysis of MI in the Republic of Moldova between 2000 and 2019. In the descriptive retrospective epidemiological study were analysed the total MI incidence of a population of 100,000 people, the number of cases in urban and rural areas, the morbidity rate among 1000 children aged between 0 and 17 years, and patients’ age structure. Results. A decreased incidence, without cyclicity, was registered over the past 5 years from 2.57 to 0.55-1.01 per 100,000. The number of carriers accounted for 0.48-0.26 per 100,000 between 2000 and 2005, and zero during 2016-2019. MI vaccination is not carried out. The MI incidence in urban and rural areas was the same. In children aged between 0 and 17 years, during 2000 and 2005, MI incidence was 0.05–0.07, compared to 2016–2019 when it constituted 0.02–0.04 per 1000. In children aged between 0 and 2 years these indices were 0.08 per 1000 in 2004, and 0.44 per 1000 in 2018. Thus, the indices were lower among children aged between 3 and 6 years. Conclusions. Incomplete detection of MI has been noted. Children aged between 0 and 2 years are prone to develop MI, the most vulnerable ones being children aged up to one year. The age structure of patients depends on the intensity of the epidemic process. Hence, it is necessary to improve MI surveillance with genotyping of circulating strains.
format	article
author	Victoria BUCOV Alexei CEBAN Ludmila BIRCA
author_facet	Victoria BUCOV Alexei CEBAN Ludmila BIRCA
author_sort	Victoria BUCOV
title	Characteristics of meningococcal infection morbidity in the Republic of Moldova over the period 2000-2019
title_short	Characteristics of meningococcal infection morbidity in the Republic of Moldova over the period 2000-2019
title_full	Characteristics of meningococcal infection morbidity in the Republic of Moldova over the period 2000-2019
title_fullStr	Characteristics of meningococcal infection morbidity in the Republic of Moldova over the period 2000-2019
title_full_unstemmed	Characteristics of meningococcal infection morbidity in the Republic of Moldova over the period 2000-2019
title_sort	characteristics of meningococcal infection morbidity in the republic of moldova over the period 2000-2019
publisher	Asociatia de Biosiguranta si Biosecuritate
publishDate	2020
url	https://doaj.org/article/cfcf6ebe020946ada9fc0e689b54bcc1
work_keys_str_mv	AT victoriabucov characteristicsofmeningococcalinfectionmorbidityintherepublicofmoldovaovertheperiod20002019 AT alexeiceban characteristicsofmeningococcalinfectionmorbidityintherepublicofmoldovaovertheperiod20002019 AT ludmilabirca characteristicsofmeningococcalinfectionmorbidityintherepublicofmoldovaovertheperiod20002019
_version_	1718391634958221312

Characteristics of meningococcal infection morbidity in the Republic of Moldova over the period 2000-2019

Ejemplares similares