Fast mapping of short sequences with mismatches, insertions and deletions using index structures.

With few exceptions, current methods for short read mapping make use of simple seed heuristics to speed up the search. Most of the underlying matching models neglect the necessity to allow not only mismatches, but also insertions and deletions. Current evaluations indicate, however, that very differ...

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Autores principales: Steve Hoffmann, Christian Otto, Stefan Kurtz, Cynthia M Sharma, Philipp Khaitovich, Jörg Vogel, Peter F Stadler, Jörg Hackermüller
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
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Acceso en línea:https://doaj.org/article/cfd4781c4e6c4148862bdfe485b4cc03
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