Highly Elastic Super-Macroporous Cryogels Fabricated by Thermally Induced Crosslinking of 2-Hydroxyethylcellulose with Citric Acid in Solid State

Biopolymer materials have been considered a “green” alternative to petroleum-based polymeric materials. Biopolymers cannot completely replace synthetic polymers, but their application should be extended as much as possible, exploiting the benefits of their low toxicity and biodegradability. This con...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Nadegda Bozova, Petar D. Petrov
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	cryogels 2-hydroxyethylcellulose citric acid green materials Organic chemistry QD241-441
Acceso en línea:	https://doaj.org/article/cfd64205a5a647a3a22b766640736b22
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:cfd64205a5a647a3a22b766640736b22
record_format	dspace
spelling	oai:doaj.org-article:cfd64205a5a647a3a22b766640736b222021-11-11T18:24:03ZHighly Elastic Super-Macroporous Cryogels Fabricated by Thermally Induced Crosslinking of 2-Hydroxyethylcellulose with Citric Acid in Solid State10.3390/molecules262163701420-3049https://doaj.org/article/cfd64205a5a647a3a22b766640736b222021-10-01T00:00:00Zhttps://www.mdpi.com/1420-3049/26/21/6370https://doaj.org/toc/1420-3049Biopolymer materials have been considered a “green” alternative to petroleum-based polymeric materials. Biopolymers cannot completely replace synthetic polymers, but their application should be extended as much as possible, exploiting the benefits of their low toxicity and biodegradability. This contribution describes a novel strategy for the synthesis of super-macroporous 2-hydroxyethylcellulose (HEC) cryogels. The method involves cryogenic treatment of an aqueous solution of HEC and citric acid (CA), freeze drying, and thermally induced crosslinking of HEC macrochains by CA in a solid state. The effect of reaction temperature (70–180 °C) and CA concentration (5–20 mass % to HEC) on the reaction efficacy and physico-mechanical properties of materials was investigated. Highly elastic cryogels were fabricated, with crosslinking carried out at ≥100 °C. The storage modulus of the newly obtained HEC cryogels was ca. 20 times higher than the modulus of pure HEC cryogels prepared by photochemical crosslinking. HEC cryogels possess an open porous structure, as confirmed by scanning electron microscopy (SEM), and uptake a relatively large amount of water. The swelling degree varied between 17 and 40, depending on the experimental conditions. The degradability of HEC cryogels was demonstrated by acid hydrolysis experiments.Nadegda BozovaPetar D. PetrovMDPI AGarticlecryogels2-hydroxyethylcellulosecitric acidgreen materialsOrganic chemistryQD241-441ENMolecules, Vol 26, Iss 6370, p 6370 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cryogels 2-hydroxyethylcellulose citric acid green materials Organic chemistry QD241-441
spellingShingle	cryogels 2-hydroxyethylcellulose citric acid green materials Organic chemistry QD241-441 Nadegda Bozova Petar D. Petrov Highly Elastic Super-Macroporous Cryogels Fabricated by Thermally Induced Crosslinking of 2-Hydroxyethylcellulose with Citric Acid in Solid State
description	Biopolymer materials have been considered a “green” alternative to petroleum-based polymeric materials. Biopolymers cannot completely replace synthetic polymers, but their application should be extended as much as possible, exploiting the benefits of their low toxicity and biodegradability. This contribution describes a novel strategy for the synthesis of super-macroporous 2-hydroxyethylcellulose (HEC) cryogels. The method involves cryogenic treatment of an aqueous solution of HEC and citric acid (CA), freeze drying, and thermally induced crosslinking of HEC macrochains by CA in a solid state. The effect of reaction temperature (70–180 °C) and CA concentration (5–20 mass % to HEC) on the reaction efficacy and physico-mechanical properties of materials was investigated. Highly elastic cryogels were fabricated, with crosslinking carried out at ≥100 °C. The storage modulus of the newly obtained HEC cryogels was ca. 20 times higher than the modulus of pure HEC cryogels prepared by photochemical crosslinking. HEC cryogels possess an open porous structure, as confirmed by scanning electron microscopy (SEM), and uptake a relatively large amount of water. The swelling degree varied between 17 and 40, depending on the experimental conditions. The degradability of HEC cryogels was demonstrated by acid hydrolysis experiments.
format	article
author	Nadegda Bozova Petar D. Petrov
author_facet	Nadegda Bozova Petar D. Petrov
author_sort	Nadegda Bozova
title	Highly Elastic Super-Macroporous Cryogels Fabricated by Thermally Induced Crosslinking of 2-Hydroxyethylcellulose with Citric Acid in Solid State
title_short	Highly Elastic Super-Macroporous Cryogels Fabricated by Thermally Induced Crosslinking of 2-Hydroxyethylcellulose with Citric Acid in Solid State
title_full	Highly Elastic Super-Macroporous Cryogels Fabricated by Thermally Induced Crosslinking of 2-Hydroxyethylcellulose with Citric Acid in Solid State
title_fullStr	Highly Elastic Super-Macroporous Cryogels Fabricated by Thermally Induced Crosslinking of 2-Hydroxyethylcellulose with Citric Acid in Solid State
title_full_unstemmed	Highly Elastic Super-Macroporous Cryogels Fabricated by Thermally Induced Crosslinking of 2-Hydroxyethylcellulose with Citric Acid in Solid State
title_sort	highly elastic super-macroporous cryogels fabricated by thermally induced crosslinking of 2-hydroxyethylcellulose with citric acid in solid state
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/cfd64205a5a647a3a22b766640736b22
work_keys_str_mv	AT nadegdabozova highlyelasticsupermacroporouscryogelsfabricatedbythermallyinducedcrosslinkingof2hydroxyethylcellulosewithcitricacidinsolidstate AT petardpetrov highlyelasticsupermacroporouscryogelsfabricatedbythermallyinducedcrosslinkingof2hydroxyethylcellulosewithcitricacidinsolidstate
_version_	1718431851973967872

Highly Elastic Super-Macroporous Cryogels Fabricated by Thermally Induced Crosslinking of 2-Hydroxyethylcellulose with Citric Acid in Solid State

Ejemplares similares