Current opinions on the mechanism, classification, imaging diagnosis and treatment of post-traumatic osteomyelitis

Post-traumatic osteomyelitis (PTO) is a worldwide problem in the field of orthopaedic trauma. So far, there is no ideal treatment or consensus-based gold standard for its management. This paper reviews the representative literature focusing on PTO, mainly from the following four aspects: (1) the pat...

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Autores principales:	Jian Yang, Jiang-Ling Yao, Zi-Quan Wu, De-Lu Zeng, Lin-Yang Zheng, Dong Chen, Zheng-Dong Guo, Lei Peng
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Osteomyelitis Bone infection Post-traumatic osteomyelitis Pathology Diagnosis Clinical classification Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/cfdc14c3431246979ca3985f4059e457
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spelling	oai:doaj.org-article:cfdc14c3431246979ca3985f4059e4572021-11-18T04:43:45ZCurrent opinions on the mechanism, classification, imaging diagnosis and treatment of post-traumatic osteomyelitis1008-127510.1016/j.cjtee.2021.07.006https://doaj.org/article/cfdc14c3431246979ca3985f4059e4572021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1008127521001188https://doaj.org/toc/1008-1275Post-traumatic osteomyelitis (PTO) is a worldwide problem in the field of orthopaedic trauma. So far, there is no ideal treatment or consensus-based gold standard for its management. This paper reviews the representative literature focusing on PTO, mainly from the following four aspects: (1) the pathophysiological mechanism of PTO and the interaction mechanism between bacteria and the body, including fracture stress, different components of internal fixation devices, immune response, occurrence and development mechanisms of inflammation in PTO, as well as the occurrence and development mechanisms of PTO in skeletal system; (2) clinical classification, mainly the etiological classification, histological classification, anatomical classification and the newly proposed new classifications (a brief analysis of their scope and limitations); (3) imaging diagnosis, including non-invasive examination and invasive examination (this paper discusses their advantages and disadvantages respectively, and briefly compares the sensitivity and effectiveness of the current examinations); and (4) strategies, including antibiotic administration, surgical choices and other treatment programs. Based on the above-mentioned four aspects, we try to put forward some noteworthy sections, in order to make the existing opinions more specific.Jian YangJiang-Ling YaoZi-Quan WuDe-Lu ZengLin-Yang ZhengDong ChenZheng-Dong GuoLei PengElsevierarticleOsteomyelitisBone infectionPost-traumatic osteomyelitisPathologyDiagnosisClinical classificationMedicine (General)R5-920ENChinese Journal of Traumatology, Vol 24, Iss 6, Pp 320-327 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Osteomyelitis Bone infection Post-traumatic osteomyelitis Pathology Diagnosis Clinical classification Medicine (General) R5-920
spellingShingle	Osteomyelitis Bone infection Post-traumatic osteomyelitis Pathology Diagnosis Clinical classification Medicine (General) R5-920 Jian Yang Jiang-Ling Yao Zi-Quan Wu De-Lu Zeng Lin-Yang Zheng Dong Chen Zheng-Dong Guo Lei Peng Current opinions on the mechanism, classification, imaging diagnosis and treatment of post-traumatic osteomyelitis
description	Post-traumatic osteomyelitis (PTO) is a worldwide problem in the field of orthopaedic trauma. So far, there is no ideal treatment or consensus-based gold standard for its management. This paper reviews the representative literature focusing on PTO, mainly from the following four aspects: (1) the pathophysiological mechanism of PTO and the interaction mechanism between bacteria and the body, including fracture stress, different components of internal fixation devices, immune response, occurrence and development mechanisms of inflammation in PTO, as well as the occurrence and development mechanisms of PTO in skeletal system; (2) clinical classification, mainly the etiological classification, histological classification, anatomical classification and the newly proposed new classifications (a brief analysis of their scope and limitations); (3) imaging diagnosis, including non-invasive examination and invasive examination (this paper discusses their advantages and disadvantages respectively, and briefly compares the sensitivity and effectiveness of the current examinations); and (4) strategies, including antibiotic administration, surgical choices and other treatment programs. Based on the above-mentioned four aspects, we try to put forward some noteworthy sections, in order to make the existing opinions more specific.
format	article
author	Jian Yang Jiang-Ling Yao Zi-Quan Wu De-Lu Zeng Lin-Yang Zheng Dong Chen Zheng-Dong Guo Lei Peng
author_facet	Jian Yang Jiang-Ling Yao Zi-Quan Wu De-Lu Zeng Lin-Yang Zheng Dong Chen Zheng-Dong Guo Lei Peng
author_sort	Jian Yang
title	Current opinions on the mechanism, classification, imaging diagnosis and treatment of post-traumatic osteomyelitis
title_short	Current opinions on the mechanism, classification, imaging diagnosis and treatment of post-traumatic osteomyelitis
title_full	Current opinions on the mechanism, classification, imaging diagnosis and treatment of post-traumatic osteomyelitis
title_fullStr	Current opinions on the mechanism, classification, imaging diagnosis and treatment of post-traumatic osteomyelitis
title_full_unstemmed	Current opinions on the mechanism, classification, imaging diagnosis and treatment of post-traumatic osteomyelitis
title_sort	current opinions on the mechanism, classification, imaging diagnosis and treatment of post-traumatic osteomyelitis
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/cfdc14c3431246979ca3985f4059e457
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Current opinions on the mechanism, classification, imaging diagnosis and treatment of post-traumatic osteomyelitis

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