<italic toggle="yes">Candida albicans</italic> Genetic Background Influences Mean and Heterogeneity of Drug Responses and Genome Stability during Evolution in Fluconazole

<italic toggle="yes">Candida albicans</italic> Genetic Background Influences Mean and Heterogeneity of Drug Responses and Genome Stability during Evolution in Fluconazole

ABSTRACT The importance of within-species diversity in determining the evolutionary potential of a population to evolve drug resistance or tolerance is not well understood, including in eukaryotic pathogens. To examine the influence of genetic background, we evolved replicates of 20 different clinic...

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Detalles Bibliográficos
Autores principales: Aleeza C. Gerstein, Judith Berman
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
AMR
fitness
ploidy
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/cff38336b5c6482a97784e6d6503f8b2
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