Relationship between hair cortisol concentrations and depressive symptoms in patients with coronary artery disease

Yekta Dowlati1,3, Nathan Herrmann2,3, Walter Swardfager1,3, Steven Thomson4, Paul I Oh3,5, Stan Van Uum4, Gideon Koren1,4, Krista L Lanct&ocirc;t1,2,3,51Departments of Pharmacology and Toxicology and 2Psychiatry, University of Toronto; 3Sunnybrook Health Sciences Centre, 4Department of Medic...

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Autores principales:	Yekta Dowlati, Nathan Herrmann, Walter Swardfager, et al
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/cff4fadb9311445e86ed53c8e302ce43
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spelling	oai:doaj.org-article:cff4fadb9311445e86ed53c8e302ce432021-12-02T06:25:45ZRelationship between hair cortisol concentrations and depressive symptoms in patients with coronary artery disease1176-63281178-2021https://doaj.org/article/cff4fadb9311445e86ed53c8e302ce432010-06-01T00:00:00Zhttp://www.dovepress.com/relationship-between-hair-cortisol-concentrations-and-depressive-sympt-a4665https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Yekta Dowlati1,3, Nathan Herrmann2,3, Walter Swardfager1,3, Steven Thomson4, Paul I Oh3,5, Stan Van Uum4, Gideon Koren1,4, Krista L Lanct&ocirc;t1,2,3,51Departments of Pharmacology and Toxicology and 2Psychiatry, University of Toronto; 3Sunnybrook Health Sciences Centre, 4Department of Medicine, University of Western Ontario; 5Toronto Rehabilitation Institute, Ontario, CanadaObjective: Concentrations of cortisol in hair, a novel marker of longer-term cortisol status, were compared in depressed versus nondepressed patients with coronary artery disease (CAD).Methods: 20 mg hair samples of 3 cm length were collected from 121 patients attending a cardiac rehabilitation program, 34 of whom suffered from depressive symptoms.Results: Controlling for age, gender, coronary artery bypass grafting, history of depression, and time since most recent acute coronary syndrome, cortisol concentrations (P = 0.162) did not predict severity of depression. Younger age (P = 0.003) was a significant predictor of depressive symptoms. Perceived stress was not associated with long-term cortisol concentrations (P = 0.161).Conclusions: Cortisol concentrations in hair do not predict depressive symptoms in CAD patients attending cardiac rehabilitation.Keywords: cortisol, depression, hair, coronary artery disease Yekta DowlatiNathan HerrmannWalter Swardfageret alDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2010, Iss Issue 1, Pp 393-400 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Yekta Dowlati Nathan Herrmann Walter Swardfager et al Relationship between hair cortisol concentrations and depressive symptoms in patients with coronary artery disease
description	Yekta Dowlati1,3, Nathan Herrmann2,3, Walter Swardfager1,3, Steven Thomson4, Paul I Oh3,5, Stan Van Uum4, Gideon Koren1,4, Krista L Lanct&ocirc;t1,2,3,51Departments of Pharmacology and Toxicology and 2Psychiatry, University of Toronto; 3Sunnybrook Health Sciences Centre, 4Department of Medicine, University of Western Ontario; 5Toronto Rehabilitation Institute, Ontario, CanadaObjective: Concentrations of cortisol in hair, a novel marker of longer-term cortisol status, were compared in depressed versus nondepressed patients with coronary artery disease (CAD).Methods: 20 mg hair samples of 3 cm length were collected from 121 patients attending a cardiac rehabilitation program, 34 of whom suffered from depressive symptoms.Results: Controlling for age, gender, coronary artery bypass grafting, history of depression, and time since most recent acute coronary syndrome, cortisol concentrations (P = 0.162) did not predict severity of depression. Younger age (P = 0.003) was a significant predictor of depressive symptoms. Perceived stress was not associated with long-term cortisol concentrations (P = 0.161).Conclusions: Cortisol concentrations in hair do not predict depressive symptoms in CAD patients attending cardiac rehabilitation.Keywords: cortisol, depression, hair, coronary artery disease
format	article
author	Yekta Dowlati Nathan Herrmann Walter Swardfager et al
author_facet	Yekta Dowlati Nathan Herrmann Walter Swardfager et al
author_sort	Yekta Dowlati
title	Relationship between hair cortisol concentrations and depressive symptoms in patients with coronary artery disease
title_short	Relationship between hair cortisol concentrations and depressive symptoms in patients with coronary artery disease
title_full	Relationship between hair cortisol concentrations and depressive symptoms in patients with coronary artery disease
title_fullStr	Relationship between hair cortisol concentrations and depressive symptoms in patients with coronary artery disease
title_full_unstemmed	Relationship between hair cortisol concentrations and depressive symptoms in patients with coronary artery disease
title_sort	relationship between hair cortisol concentrations and depressive symptoms in patients with coronary artery disease
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/cff4fadb9311445e86ed53c8e302ce43
work_keys_str_mv	AT yektadowlati relationshipbetweenhaircortisolconcentrationsanddepressivesymptomsinpatientswithcoronaryarterydisease AT nathanherrmann relationshipbetweenhaircortisolconcentrationsanddepressivesymptomsinpatientswithcoronaryarterydisease AT walterswardfager relationshipbetweenhaircortisolconcentrationsanddepressivesymptomsinpatientswithcoronaryarterydisease AT etal relationshipbetweenhaircortisolconcentrationsanddepressivesymptomsinpatientswithcoronaryarterydisease
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Relationship between hair cortisol concentrations and depressive symptoms in patients with coronary artery disease

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