Prophages and Growth Dynamics Confound Experimental Results with Antibiotic-Tolerant Persister Cells

ABSTRACT Bacterial persisters are phenotypic variants that survive antibiotic treatment in a dormant state and can be formed by multiple pathways. We recently proposed that the second messenger (p)ppGpp drives Escherichia coli persister formation through protease Lon and activation of toxin-antitoxi...

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Auteurs principaux: Alexander Harms, Cinzia Fino, Michael A. Sørensen, Szabolcs Semsey, Kenn Gerdes
Format: article
Langue:EN
Publié: American Society for Microbiology 2017
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Accès en ligne:https://doaj.org/article/cffbb0425c894b5f986f76f39f6649e9
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