CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient
WUSCHEL is a critical regulator of stem cell homeostasis at shoot apical meristems. Here the authors show that CLV3 regulates WUSCHEL by not only repressing WUSCHEL transcription but also by controlling nuclear export of WUSCHEL and therefore its diffusion between adjacent cells.
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Nature Portfolio
2021
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oai:doaj.org-article:cffd650ae02949aab19a9a0a6860b1fb2021-11-08T11:11:11ZCLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient10.1038/s41467-021-26586-02041-1723https://doaj.org/article/cffd650ae02949aab19a9a0a6860b1fb2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26586-0https://doaj.org/toc/2041-1723WUSCHEL is a critical regulator of stem cell homeostasis at shoot apical meristems. Here the authors show that CLV3 regulates WUSCHEL by not only repressing WUSCHEL transcription but also by controlling nuclear export of WUSCHEL and therefore its diffusion between adjacent cells.Alexander PlongKevin RodriguezMark AlberWeitao ChenG. Venugopala ReddyNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021) |
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Science Q Alexander Plong Kevin Rodriguez Mark Alber Weitao Chen G. Venugopala Reddy CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient |
description |
WUSCHEL is a critical regulator of stem cell homeostasis at shoot apical meristems. Here the authors show that CLV3 regulates WUSCHEL by not only repressing WUSCHEL transcription but also by controlling nuclear export of WUSCHEL and therefore its diffusion between adjacent cells. |
format |
article |
author |
Alexander Plong Kevin Rodriguez Mark Alber Weitao Chen G. Venugopala Reddy |
author_facet |
Alexander Plong Kevin Rodriguez Mark Alber Weitao Chen G. Venugopala Reddy |
author_sort |
Alexander Plong |
title |
CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient |
title_short |
CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient |
title_full |
CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient |
title_fullStr |
CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient |
title_full_unstemmed |
CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient |
title_sort |
clavata3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the wuschel gradient |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/cffd650ae02949aab19a9a0a6860b1fb |
work_keys_str_mv |
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1718442378068492288 |